A potential role for olanzapine in the treatment of hyperemesis gravidarum

Verinder Sharma, Sapna Sharma, J. Hutson, Alex Martín
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引用次数: 1

Abstract

Abstract Hyperemesis gravidarum is a rare but potentially serious complication of pregnancy. Some women with severe symptoms and possibly psychiatric comorbidities remain symptomatic despite the use of currently available treatments. Due to its favorable safety profile, antiemetic efficacy in other conditions, and 5-HT3 antagonism, olanzapine may be a potentially useful addition to the armamentarium for management of hyperemesis gravidarum resistant to standard- of-care treatment.
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奥氮平治疗妊娠剧吐的潜在作用
摘要妊娠剧吐是一种罕见但潜在严重的妊娠并发症。一些有严重症状和可能有精神合并症的妇女尽管使用了目前可用的治疗方法,但仍有症状。由于其良好的安全性,在其他情况下的止吐效果,以及5-HT3的拮抗作用,奥氮平可能是治疗对标准治疗耐药的妊娠剧吐的潜在有用的补充。
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