Current Scenario of Oppoutunistic Fungal Infections other than the Candida and Aspergillus Species, their correlation and Outcome with the CD4+T Cell Counts among Various Respiratory Samples in Immuno Competent and Immunocomporomised Individuals in Aligarh Region, A North India Town

Abstract

Introduction: Invasive fungal infections other than the Candida species and Aspergillus species are becoming common in the nosocomial setting particularly among the immunocompromised patients but there is a hinderance in their accurate diagnosis. Aim of our study was to know the prevalence of rare fungal species and to know the patients outcome in our region. Aim of our study is to know the prevalence of rare fungal species and to know the patients outcome in our region. Material amd Methods: The present study was carried out on the patients attending outpatient department and inpatient department of T.B. and Respiratory Diseases, along with those attending antiretroviral treatment clinic and ICTC (Department of Microbiology), in J. N. Medical College, AMU during the period of January 2015 to October 2016. Results: Majority of the cases i.e., 47 (31.3%) were between 31-40 years with a mean age of 32.5 years. Of 65 isolates, Cryptococcus neoformans and Pneumocystis jirovecii represented 2 (6.1%) isolates each, all of which were found in HIV positive cases. 1 (3.1%) isolate of Mucor from a diabetic patient and 1 (3.1%) isolate of Penicillium marneffei from an HIV positive patient as detected. Cryptococcus and Pneumocystis jirovecii were isolated from both patients with CD4 count< 200. and 114(+19.9) respectively. Conclusions: Invasive fungal infections other than the candidia species and aspergillus species are becoming very common now a days.