Synthesis, Reactions and Medicinal Importance of Cyclic Sulfone Derivatives: A Review

M. A. Alam, K. Shimada, Aklima Jahan, M. Khan, M. H. Bhuiyan, M. Alam, M. Matin
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引用次数: 2

Abstract

Sulfones or the cyclic sulfones are the type of organosulfur compounds that attract the special interest to organic chemists. Vast applications are observed in different fields with these types of sulfone containing compounds and their derivatives like in medicinal chemistry and also give the importance to many kinds of biological activity. The sulfones and their derivatives are used in many other fields as pharmaceutical and polymeric agents. Sulfone containing compounds are also used for the treatment of different diseases like dermatitis herpetiformis, leprosy, tuberculosis and others. The researchers have been giving much concentration to synthesize many types of sulfone compounds because of their various strong medicinal activities like as biological, antimalarial, antimicrobial, antiinflammatory, anticancer, anti-HIV, and anti-inflammatory and in other sectors also. These kinds of vast importance encourage us to study about the synthesis, reactions and applications of cyclic sulfones and their derivatives. The present article will provide some important information about the synthesis, reactions and applications of cyclic sulfone type compounds to the chemists to facilitate them in advance research works with more concentration which will be more beneficial for the society as well as for upcoming science generation.
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环砜衍生物的合成、反应及药用价值综述
砜或环砜是一类有机硫化合物,引起了有机化学家的特别兴趣。这类含砜类化合物及其衍生物在药物化学等不同领域有着广泛的应用,并对多种生物活性具有重要意义。砜及其衍生物在许多其他领域被用作药物和聚合剂。含有砜的化合物也用于治疗各种疾病,如疱疹样皮炎、麻风病、肺结核等。由于砜类化合物具有生物、抗疟、抗菌、抗炎、抗癌、抗艾滋病毒、抗炎等多种强大的药用活性,研究人员一直致力于合成多种类型的砜类化合物。这些巨大的重要性促使我们对环砜及其衍生物的合成、反应和应用进行研究。本文将提供环砜类化合物的合成、反应和应用方面的一些重要信息,以方便化学家们更专心地进行前期研究工作,更有利于社会和下一代的科学发展。
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