Percuteneous Trans-Mitral Commissurotomy (PTMC); Procedural Success and Immediate Results, an Experience from Tertiary Care Hospital in Northern Division of Bangladesh

Md. Mahbubur Rahman, S. Ghafur, R. Barman, H. Sarkar, Abu Zahid Basunia, Md Hasanul Islam, A. Mahmud
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引用次数: 1

Abstract

Background: One of the ultimate grave consequences of rheumatic heart disease is mitral stenosis. Percutaneous trans-mitral commissurotomy (PTMC) has been practiced with good results in the world since Inoue introduced it in 1982. Objective: The aim of this study was to audit the procedural success, in- hospital outcome in patients undergoing PTMC in our set up. Study Design: Observational cross sectional study. Place and Duration: The study was conducted in northern division of Bangladesh with the collaboration of department of cardiology, Rangpur Medical College Hospital, Rangpur & Zia Heart Foundation, Dinazpur from February 2018 to November 2019. Materials and Methods: Total Thirty patients who fulfill the inclusion and exclusion criteria for PTMC was enrolled in this study. Among them the procedural success & immediate results were assessed. Results: Among 30 patients , 22(73.33%) were female and 8(26.66%) were male showing a female predominance. The mean age was 28.28±8.4.The procedure was successful in 29(96.66%) patients. In 1(3.3%) patient, we failed due to inability to puncture the septum for unfavourable anatomy. There was no mortality related to the procedure, no systemic embolization but one patient (3.33%) had significant MR(G II ). Pre PTMC mean MVA (cm2) was 0.801± 0.1325 and post PTMC it was 1.545± 0.292 cm2. Mean MVPG pre PTMC was 27.108±5.94 mmHg and post PTMC , 6.61±5.008 mmHg with significant p value 0.0001. Mean LA pressure before procedure was 28.65±8.456 mmHg and post PTMC, 11.27±6.34 and p value was 0.0001. Most of the patients 25(83.3%) before PTMC were in severe pulmonary hypertension and after PTMC most of the patients 21(70%) were in mild pulmonary hypertension.We successfully done 7 special cases like pregnancy, re do cases, H/O CVD etc. Conclusions: We conclude that PTMC is a safe procedure in experienced hand with good success rate and optimal results even in patients with special problems like pregnancy, previous CVA and redo cases. University Heart Journal Vol. 17, No. 1, Jan 2021; 47-54
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经皮二尖瓣合拢切开术;手术成功和立竿见影——孟加拉国北部地区三级医院的经验
背景:风湿性心脏病的最终严重后果之一是二尖瓣狭窄。自1982年Inoue提出经皮二尖瓣合心术(PTMC)以来,在世界范围内进行了实践,并取得了良好的效果。目的:本研究的目的是审核我院PTMC患者的手术成功率和住院结果。研究设计:观察性横断面研究。地点和时间:该研究于2018年2月至2019年11月在孟加拉国北部地区与迪纳兹普尔Rangpur医学院医院心内科,Rangpur & Zia心脏基金会合作进行。材料与方法:本研究共纳入30例符合PTMC纳入和排除标准的患者。其中对程序成功和即时效果进行了评估。结果:30例患者中,女性22例(73.33%),男性8例(26.66%),以女性为主。平均年龄28.28±8.4岁。29例(96.66%)患者手术成功。在1例(3.3%)患者中,由于解剖结构不利,无法穿刺中隔,我们失败了。没有与手术相关的死亡率,没有全身性栓塞,但有1例(3.33%)有明显的MR(G II)。PTMC前平均MVA (cm2) 0.801±0.1325,PTMC后平均MVA (cm2) 1.545±0.292。PTMC前平均MVPG为27.108±5.94 mmHg, PTMC后平均MVPG为6.61±5.008 mmHg, p值显著性为0.0001。术前平均LA压为28.65±8.456 mmHg,术后平均LA压为11.27±6.34,p值为0.0001。PTMC前绝大多数25例(83.3%)为重度肺动脉高压,PTMC后绝大多数21例(70%)为轻度肺动脉高压。成功完成妊娠、重症肌炎、心血管疾病等特殊病例7例。结论:在经验丰富的患者中,PTMC是一种安全的手术,即使是有特殊问题的患者,如妊娠、既往CVA和重做病例,也有良好的成功率和最佳的效果。《大学心脏杂志》第17卷第1期,2021年1月;47-54
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