Lead exposures in older children (males and females 7–17 years), women of childbearing age (females 16–49 years) and adults (males and females 18+ years): FDA total diet study 2014–16

Alexandra Gavelek, J. Spungen, D. Hoffman-Pennesi, B. Flannery, L. Dolan, S. Dennis, S. Fitzpatrick
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引用次数: 7

Abstract

ABSTRACT Dietary exposures to lead were estimated for older children, females of childbearing age and adults based on lead concentration data from the FDA’s Total Diet Study and on food consumption data from What We Eat In America (WWEIA), the food survey portion of the National Health and Nutrition Examination Survey (NHANES). Estimated mean exposures varied based on the population and on the three different substitution scenarios for lead values below the limit of detection (non-detects = 0; non-detects = limit of detection; hybrid approach). Estimated mean lead exposures range from 1.4 to 4.0 µg/day for older children (males and females 7–17 years), 1.6 to 4.6 µg/day for women of childbearing age (females 16–49 years) and 1.7 to 5.3 µg/day for adults (males and females 18 years and older). Estimated 90th percentile lead exposures range from 2.3 to 5.8 µg/day for older children, 2.8 to 6.7 µg/day for women of childbearing age and 3.2 to 7.8 µg/day for adults. Exposure estimates suggest some older children may be exposed to dietary lead above the FDA interim reference level for lead in children of 3 µg/day. The results of this study can be used by the FDA to prioritise research and regulatory efforts in the area of dietary lead exposure.
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大龄儿童(男性和女性7-17岁)、育龄妇女(女性16-49岁)和成年人(男性和女性18岁以上)的铅暴露:FDA 2014-16年总饮食研究
根据FDA总饮食研究的铅浓度数据和美国国家健康与营养检查调查(NHANES)的食品调查部分“我们在美国吃什么”(WWEIA)的食品消费数据,对大龄儿童、育龄女性和成年人的饮食铅暴露进行了估计。估计的平均暴露量因人群和低于检测极限的铅值的三种不同替代方案而异(非检测= 0;未检测到=检测极限;混合方法)。年龄较大的儿童(7-17岁的男性和女性)的平均铅暴露量估计为1.4至4.0微克/天,育龄妇女(16-49岁的女性)的平均铅暴露量为1.6至4.6微克/天,成年人(18岁及以上的男性和女性)的平均铅暴露量为1.7至5.3微克/天。估计90百分位铅暴露范围为:年龄较大的儿童每天2.3至5.8微克,育龄妇女每天2.8至6.7微克,成人每天3.2至7.8微克。暴露估计表明,一些年龄较大的儿童可能暴露于超过FDA儿童铅临时参考水平3微克/天的膳食铅。这项研究的结果可以被FDA用来优先考虑饮食铅暴露领域的研究和监管工作。
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