Faiza Khatoon , Arzeena Jabeen , Qamar Uddin , Nazim Husain , Mohd Azahar , Md Sanaul Moin
{"title":"Chronic plaque psoriasis treated with topical Unani formulation Marham Ḥina – A series of case reports","authors":"Faiza Khatoon , Arzeena Jabeen , Qamar Uddin , Nazim Husain , Mohd Azahar , Md Sanaul Moin","doi":"10.1016/j.aimed.2022.06.005","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Although psoriasis<span> treatment has advanced significantly in recent years, the disease remains incurable and relapsing. Alternatively, several potent systemic and topical formulations have been described in the Unani (Greco-Arab) system of medicine for conditions clinically similar to psoriasis, but there is a dearth of scientific evidence.</span></p></div><div><h3>Aim</h3><p>The purpose of this study was to investigate the efficacy and safety of the Unani formulation Marham Ḥina in chronic plaque psoriasis.</p></div><div><h3>Methods</h3><p>Seven patients with chronic plaque psoriasis, were treated with Marham Ḥina for 12 weeks.</p></div><div><h3>Results</h3><p>The mean ± SD of the psoriasis area and severity index (PASI) was significantly decreased from 24.00 ± 10.18 at baseline to 2.00 ± 1.29. One case attained PASI 100, two cases attained PASI 95, another two cases attained PASI 90, and the remaining two cases attained PASI 75.</p></div><div><h3>Conclusion</h3><p>The trial formulation appears to have a strong anti-psoriatic effect, while posing no adverse effects. However, more precise prospective clinical studies are recommended to confirm its scientific validity</p></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in integrative medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212958822000684","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 1
Abstract
Background
Although psoriasis treatment has advanced significantly in recent years, the disease remains incurable and relapsing. Alternatively, several potent systemic and topical formulations have been described in the Unani (Greco-Arab) system of medicine for conditions clinically similar to psoriasis, but there is a dearth of scientific evidence.
Aim
The purpose of this study was to investigate the efficacy and safety of the Unani formulation Marham Ḥina in chronic plaque psoriasis.
Methods
Seven patients with chronic plaque psoriasis, were treated with Marham Ḥina for 12 weeks.
Results
The mean ± SD of the psoriasis area and severity index (PASI) was significantly decreased from 24.00 ± 10.18 at baseline to 2.00 ± 1.29. One case attained PASI 100, two cases attained PASI 95, another two cases attained PASI 90, and the remaining two cases attained PASI 75.
Conclusion
The trial formulation appears to have a strong anti-psoriatic effect, while posing no adverse effects. However, more precise prospective clinical studies are recommended to confirm its scientific validity
期刊介绍:
Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.