Chronic plaque psoriasis treated with topical Unani formulation Marham Ḥina – A series of case reports

IF 1.7 Q2 Medicine Advances in integrative medicine Pub Date : 2022-09-01 DOI:10.1016/j.aimed.2022.06.005

Faiza Khatoon , Arzeena Jabeen , Qamar Uddin , Nazim Husain , Mohd Azahar , Md Sanaul Moin

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引用次数: 1

Abstract

Background

Although psoriasis treatment has advanced significantly in recent years, the disease remains incurable and relapsing. Alternatively, several potent systemic and topical formulations have been described in the Unani (Greco-Arab) system of medicine for conditions clinically similar to psoriasis, but there is a dearth of scientific evidence.

Aim

The purpose of this study was to investigate the efficacy and safety of the Unani formulation Marham Ḥina in chronic plaque psoriasis.

Methods

Seven patients with chronic plaque psoriasis, were treated with Marham Ḥina for 12 weeks.

Results

The mean ± SD of the psoriasis area and severity index (PASI) was significantly decreased from 24.00 ± 10.18 at baseline to 2.00 ± 1.29. One case attained PASI 100, two cases attained PASI 95, another two cases attained PASI 90, and the remaining two cases attained PASI 75.

Conclusion

The trial formulation appears to have a strong anti-psoriatic effect, while posing no adverse effects. However, more precise prospective clinical studies are recommended to confirm its scientific validity

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慢性斑块型银屑病治疗局部Unani制剂Marham Ḥina -一系列病例报告

背景:尽管近年来银屑病的治疗取得了显著进展，但这种疾病仍然无法治愈并会复发。另外，在Unani(希腊-阿拉伯)医学系统中，已经描述了几种有效的全身和局部配方，用于临床类似牛皮癣的病症，但缺乏科学证据。目的探讨Unani复方Marham Ḥina治疗慢性斑块型银屑病的疗效和安全性。方法对7例慢性斑块型银屑病患者采用Marham Ḥina治疗12周。结果银屑病面积及严重程度指数(PASI)均值±SD由基线时的24.00±10.18降至2.00±1.29。1例达到PASI 100, 2例达到PASI 95, 2例达到PASI 90，其余2例达到PASI 75。结论该制剂具有较强的抗银屑病作用，且无不良反应。然而，建议更精确的前瞻性临床研究来证实其科学有效性

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来源期刊

Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

3.20

自引率

11.80%

发文量

审稿时长

15 weeks

期刊介绍： Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.