Microparticles Formulation as a Targeting Drug Delivery System

Abstract

The ideal sustained release products should not only have a prolonged drug releasing function, but should also offer once or twice a day dose treatment and better control of therapeutic drug level; this will have two benefits: the first is fewer side effects and the second is improved disease management. Hence a good patient compliance is obtained due to reduction in the frequency of daily dosing [1,2]. The problem of patient compliance and its considerable effect on drug therapy is the great advances and extensive research work considering drug absorption and its pharmacokinetics, the rapid growth of polymer technology and some other factors are behind the interest and rationale design of prolonged action dosage forms [3]. Prolonged or controlled release drugs are classified into three basic types: (1) Sustained release, (2) Prolonged action, and (3) repeat action dosage forms [4].