[Polyarteritis nodosa].

M. Murakami, S. Ozaki, K. Nakao
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Abstract

Polyarteritis nodosa (PAN) is the systemic necrotizing vasculitis on small and median muscular vessels. Recent studies reveal that PAN consists of classical PAN and microscopic polyangitis (MPA). MPO-ANCA, which is one of anti-neutrophil cytoplasmic antibody (ANCA), is involved in the pathogenesis of MPA. In future, by the progress of research of ANCA, the definition or criteria of systemic vasculitis including PAN or MPA will be changed.
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结节性多动脉炎(PAN)是发生在小血管和中肌血管上的系统性坏死性血管炎。近年来的研究表明,PAN由经典PAN和显微多血管炎(MPA)组成。MPO-ANCA是抗中性粒细胞胞浆抗体(ANCA)的一种,参与了MPA的发病过程。未来,随着ANCA研究的进展,包括PAN或MPA在内的系统性血管炎的定义或标准将会改变。
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