Parental consanguinity a possible risk factor for tooth agenesis: A case series

M. Siddiqui, A. Juneja, A. Sultan
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Abstract

Dental agenesis is a commonly encountered dental anomaly that affects more than 20% of the human population. It can be categorized as hypodontia, oligodontia, or anodontia. Oligodontia can occur either as an isolated finding or as a part of the syndrome, and the causative factor can be either environmental or genetic.: This report describes three cases of isolated, non-syndromic tooth agenesis with single/ multiple missing permanent teeth. No other associated clinical features or any systemic involvement were present in these cases, suggesting parental consanguinity as a possible etiological factor.: The purpose of this case report is to promulgate premarital counselling and health awareness programs focusing on the potential consequences of consanguineous marriages and their prevention.
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父母血缘关系是牙齿发育不全的可能危险因素:一个病例系列
牙齿发育不全是一种常见的牙齿异常,影响了超过20%的人口。它可以被分类为下颌畸形、少齿畸形或无齿畸形。少齿症既可以作为孤立的发现发生,也可以作为综合征的一部分发生,致病因素可以是环境的或遗传的。本报告描述了3例孤立的非综合征性牙齿发育不全伴单/多颗恒牙缺失的病例。在这些病例中没有其他相关的临床特征或任何全身累及,提示亲本血缘关系可能是病因。本案例报告的目的是颁布婚前咨询和健康意识方案,重点关注近亲婚姻的潜在后果及其预防。
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