Magnetic nanoparticles to improve the contrast of Magnetic Resonance Imaging

kosar eskandari
{"title":"Magnetic nanoparticles to improve the contrast of Magnetic Resonance Imaging","authors":"kosar eskandari","doi":"10.22037/AMLS.V5I1.28475","DOIUrl":null,"url":null,"abstract":"Earlier detection of diseases reduces the mortality rate.  So the development of better screening techniques could be considered as a main topic of interest. In non-invasive medical imaging, specifically in  Magnetic Resonance Imaging (MRI), conventional contrast agents do not have a good performance in imaging of some fine parts. The prosperity of preclinical researches in oncology that purpose at developing and evaluating curative strategies on samples, requires effective new functionalized contrast agents for portrayal tumor growth, monitoring the trace of a treatment and/or inducing the demolition of cancerous tumors. This study was performed by searching Nanotechnology, Molecular imaging, magnetic nanoparticles, and contrast agent nanoparticles keywords in Google scholar, Science direct, PubMed and Scopus websites in terms of content. We reviewed the recent studies about development of nanoparticles as contrast agents for medical imaging because they have a longer vascular half-life than molecular contrast agents. It could be indicate that nanoparticles are important items in increasing the contrast of the images so that even reducing the size of the magnetic nanoparticles escalates the contrast and half-life of the particles. Particles with a diameter of 10 nm have a greater half-life than particles with a diameter of 30 nm or larger. It was also found that to removing material defects or improve their biocompatibility; particles should be covered with other materials or doped with metals.","PeriodicalId":18401,"journal":{"name":"Medical laboratory sciences","volume":"41 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical laboratory sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22037/AMLS.V5I1.28475","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Earlier detection of diseases reduces the mortality rate.  So the development of better screening techniques could be considered as a main topic of interest. In non-invasive medical imaging, specifically in  Magnetic Resonance Imaging (MRI), conventional contrast agents do not have a good performance in imaging of some fine parts. The prosperity of preclinical researches in oncology that purpose at developing and evaluating curative strategies on samples, requires effective new functionalized contrast agents for portrayal tumor growth, monitoring the trace of a treatment and/or inducing the demolition of cancerous tumors. This study was performed by searching Nanotechnology, Molecular imaging, magnetic nanoparticles, and contrast agent nanoparticles keywords in Google scholar, Science direct, PubMed and Scopus websites in terms of content. We reviewed the recent studies about development of nanoparticles as contrast agents for medical imaging because they have a longer vascular half-life than molecular contrast agents. It could be indicate that nanoparticles are important items in increasing the contrast of the images so that even reducing the size of the magnetic nanoparticles escalates the contrast and half-life of the particles. Particles with a diameter of 10 nm have a greater half-life than particles with a diameter of 30 nm or larger. It was also found that to removing material defects or improve their biocompatibility; particles should be covered with other materials or doped with metals.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
磁性纳米颗粒提高磁共振成像的对比度
及早发现疾病可降低死亡率。因此,发展更好的筛选技术可以被认为是一个感兴趣的主要话题。在非侵入性医学成像中,特别是磁共振成像(MRI)中,传统的造影剂在一些精细部位的成像中表现不佳。肿瘤学临床前研究的繁荣,旨在开发和评估样本治疗策略,需要有效的新型功能化对比剂来描绘肿瘤生长,监测治疗的痕迹和/或诱导癌性肿瘤的破坏。本研究通过在Google scholar、Science direct、PubMed和Scopus网站中搜索纳米技术、分子成像、磁性纳米颗粒和造影剂纳米颗粒等关键词进行内容搜索。我们回顾了纳米颗粒作为医学成像造影剂的最新研究进展,因为它们比分子造影剂具有更长的血管半衰期。这可能表明纳米颗粒是增加图像对比度的重要因素,因此即使减小磁性纳米颗粒的尺寸也会增加颗粒的对比度和半衰期。直径为10纳米的粒子比直径为30纳米或更大的粒子的半衰期更长。还发现,去除材料缺陷或提高其生物相容性;颗粒应用其他材料覆盖或掺杂金属。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Molecular Typing of Uropathogenic Escherichia coli Strains Isolated from Patients in Gorgan by Random Amplified Polymorphic DNA-PCR (RAPD-PCR) Formulating a New Pharmaceutical Drug; Acetaminophen Tablet Containing N-acetyl Cysteine, To Alleviate the Severity of Liver Damage in Rats: Phase I, Animal Study The Expression Level of CCDC26 and FOXCUT Genes in Acute Lymphoblastic Leukemia A Review of SARS-CoV-2 Genetic and Structure: Hot Cellular Targets for Virus Entry: No Evidence of Hepatitis C Virus Infection in Individuals with Cardiovascular Disease in Mashhad
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1