Effect of Mycotoxins on the Ultrastructure of Cortical Elements in Pig Nephrons

N. V. Shakurova, E. I. Semenov, V. B. Savva, Kazan Russia biological safety»
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Abstract

reports the results of an electron microscopic study of pathomorphological changes in the kidneys of pigs exposed to the combined intoxication with fusariotoxins (T-2 toxin, deoxynivalenol, and zearalenone). Mycotoxicosis-related cytological changes of the glomeruli and proximal convoluted tubules were analyzed. A series of ultrastructural changes that occurred in the cellular elements involved in ultrafiltration and reabsorption were observed and ascribed to the development of nephropathy under chronic mycotoxication.
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真菌毒素对猪肾单位皮质元件超微结构的影响
本文报道了猪暴露于镰刀菌毒素(T-2毒素、脱氧雪腐镰刀菌醇和玉米赤霉烯酮)联合中毒后肾脏病理形态学变化的电镜研究结果。分析与真菌中毒相关的肾小球和近曲小管的细胞学变化。在参与超滤和重吸收的细胞元件中观察到一系列超微结构变化,并将其归因于慢性真菌中毒肾病的发展。
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CiteScore
0.70
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审稿时长
17 weeks
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