Insight about Colonic Microbiota Imbalance and Obesity

Abstract

Since the 1990s, nutritionists have concluded that poor food hygiene, as well as environmental and food pollution, are the cause of the major serious diseases affecting humanity: overweight and obesity, which induce persistent systemic pro-inflammatory status, and hence all complications metabolic disorders, cancers, joint diseases, skin disorders, psychological disorders. The human body hosts a large number of microbes, including bacterial, fungal and protozoal microorganisms, which together constitute our microbe. Dysbiosis, generated by a sedentary lifestyle, consuming highly industrialized food, and non-compliance with the mass program, can lead to obesity, with a decrease in quality of life and shortening it. Obesity and metabolic disorders related to obesity are characterized by specific changes in the composition and function of the human intestinal microbe. Among the possible strategies for preventing and/or treating obesity, the microbiota is intended to restore or modulate its composition by consuming probiotics, prebiotics or both (synbiotics).