Phytoconstituents and preliminary antiradical property evaluation of Baillonella toxisperma (Sapotaceae)

Kevine J.J. Dongmo, R. T. Fouedjou, B. T. Tchegnitegni, B. Ponou, R. Teponno, K. Siems, M. Melzig, L. Tapondjou
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Abstract

From the EtOAc fraction of the methanol extract of the stem barks of Baillonella toxisperma (Sapotaceae), eight compounds were isolated using column chromatography techniques. Their structures were established on the basis of 1D and 2D-NMR data and comparison with data published in the literature. The MeOH extract, n-BuOH and EtOAc fractions together with some pure compounds (4, 5, 7, 8) were screened for their radical scavenging activity using the2,2-diphenyl-1- picryl-hydrazyl-hydrate (DPPH) free radical in order to get preliminary information about the antiradical capacities of this plant.Keywords: Baillonella toxisperma;Sapotaceae; DPPH; Antiradical activity
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水仙花的植物成分及抗自由基活性初步评价
利用柱层析技术从菝葜(Baillonella toxisperma)茎皮甲醇提取物的乙酸乙酯组分中分离得到8个化合物。它们的结构是在一维和二维核磁共振数据的基础上建立的,并与文献中发表的数据进行了比较。利用2,2-二苯基-1-苦基-水合肼(DPPH)自由基对该植物的MeOH提取物、n-BuOH和EtOAc组分以及一些纯化合物(4,5,7,8)的自由基清除能力进行了筛选,以初步了解该植物的抗自由基能力。毕业论文关键词:毒蝇;蜜桃科;DPPH;反激进主义的活动
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