{"title":"Misery of Long Haulers of COVID-19 - A Review","authors":"Pragi, Varun Kumar, Deepak Garg","doi":"10.2174/2667337109666230301145233","DOIUrl":null,"url":null,"abstract":"\n\nEarly in December 2019, Wuhan City, Hubei Province, China, had an epidemic of the Coronavirus illness 2019 (COVID-19), which was brought on by a brand-new severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). The epidemic was deemed a Public Health Emergency of International Concern by the World Health Organization on January 30, 2020. Many governments have implemented a range of control measures as a result of perceived illness risk.\n\n\n\nThe pandemic revealed that COVID-19 affects a variety of organs in addition to the lungs, including the heart and brain, raising the risk of long-term health consequences. The illness can affect someone's health even after recovery in a variety of ways. The long-term effects of COVID-19 on locals are still being researched. The objective is to compile knowledge regarding the virus and the present Post pandemic complications in Long Haulers.\n\n\n\nWe reviewed the body of publicly available literature. To discover publications published between December 2019 and October 2020, we conducted a systematic search utilizing the keywords in online databases such as Pub Med, Scopus, Science Direct, Up to Date, and Web of Science. The review includes peer-reviewed original publications published that matched the qualifying requirements.\n\n\n\nAlthough the majority of patients recovered quickly after receiving COVID-19, the possibility of long-term issues induced by COVID-19 necessitates the search for and research of its late consequences. This article aims to provide a comprehensive assessment of COVID-19 late complications in order to determine how prevalent these symptoms are and who is most likely to be impacted.\n\n\n\nThere are a number of difficulties with the COVID-19 pandemic that has yet to be resolved. Review of the literature reported several long-lasting clinical problems that affect different phases of health, including chronic fatigue, reduced physical capacity, muscle weakness, increased depression, anxiety, post-traumatic stress disorder and sleep problems. A complete turndown in quality of life has been observed even one year after major Coronavirus outbreaks. \nThe pandemic revealed that COVID-19 affects a variety of organs in addition to the lungs, including the heart and brain, raising the risk of long-term health consequences even after years making them to be “Long Haulers”.\nThe causal agent, pathogenesis, immunological responses, epidemiology, diagnosis, therapy, and management of the disease, as well as control and preventive efforts, are all included in this review of the literature.\n","PeriodicalId":72255,"journal":{"name":"Applied drug research, clinical trials and regulatory affairs","volume":"8 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied drug research, clinical trials and regulatory affairs","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2667337109666230301145233","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Early in December 2019, Wuhan City, Hubei Province, China, had an epidemic of the Coronavirus illness 2019 (COVID-19), which was brought on by a brand-new severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). The epidemic was deemed a Public Health Emergency of International Concern by the World Health Organization on January 30, 2020. Many governments have implemented a range of control measures as a result of perceived illness risk.
The pandemic revealed that COVID-19 affects a variety of organs in addition to the lungs, including the heart and brain, raising the risk of long-term health consequences. The illness can affect someone's health even after recovery in a variety of ways. The long-term effects of COVID-19 on locals are still being researched. The objective is to compile knowledge regarding the virus and the present Post pandemic complications in Long Haulers.
We reviewed the body of publicly available literature. To discover publications published between December 2019 and October 2020, we conducted a systematic search utilizing the keywords in online databases such as Pub Med, Scopus, Science Direct, Up to Date, and Web of Science. The review includes peer-reviewed original publications published that matched the qualifying requirements.
Although the majority of patients recovered quickly after receiving COVID-19, the possibility of long-term issues induced by COVID-19 necessitates the search for and research of its late consequences. This article aims to provide a comprehensive assessment of COVID-19 late complications in order to determine how prevalent these symptoms are and who is most likely to be impacted.
There are a number of difficulties with the COVID-19 pandemic that has yet to be resolved. Review of the literature reported several long-lasting clinical problems that affect different phases of health, including chronic fatigue, reduced physical capacity, muscle weakness, increased depression, anxiety, post-traumatic stress disorder and sleep problems. A complete turndown in quality of life has been observed even one year after major Coronavirus outbreaks.
The pandemic revealed that COVID-19 affects a variety of organs in addition to the lungs, including the heart and brain, raising the risk of long-term health consequences even after years making them to be “Long Haulers”.
The causal agent, pathogenesis, immunological responses, epidemiology, diagnosis, therapy, and management of the disease, as well as control and preventive efforts, are all included in this review of the literature.
2019年12月初,中国湖北省武汉市爆发了由新型严重急性呼吸系统综合征冠状病毒2型(SARS-CoV-2)引发的2019冠状病毒病(COVID-19)疫情。2020年1月30日,世界卫生组织将新冠肺炎疫情列为国际关注的突发公共卫生事件。许多国家的政府已经实施了一系列控制措施,以应对可能出现的疾病风险。大流行表明,COVID-19除肺部外还会影响心脏和大脑等多种器官,从而增加了长期健康后果的风险。即使在康复后,这种疾病也会以各种方式影响一个人的健康。COVID-19对当地人的长期影响仍在研究中。目的是汇编关于病毒和目前长途运输者大流行后并发症的知识。我们查阅了大量的公开文献。为了发现2019年12月至2020年10月之间发表的出版物,我们利用Pub Med、Scopus、Science Direct、Up To Date和Web of Science等在线数据库中的关键词进行了系统搜索。该审查包括同行评审的原始出版物,出版符合资格要求。虽然大多数患者在感染COVID-19后很快康复,但由于COVID-19可能引发长期问题,因此需要寻找和研究其后期后果。本文旨在全面评估COVID-19晚期并发症,以确定这些症状的普遍程度以及最有可能受到影响的人群。COVID-19大流行的一些困难尚未解决。文献综述报告了影响不同健康阶段的几个长期临床问题,包括慢性疲劳、体能下降、肌肉无力、抑郁加剧、焦虑、创伤后应激障碍和睡眠问题。甚至在冠状病毒大爆发一年后,人们的生活质量也完全下降了。大流行表明,COVID-19除了影响肺部外,还会影响心脏和大脑等多种器官,即使在多年后使它们成为“长途跋涉者”,也会增加长期健康后果的风险。病因,发病机制,免疫反应,流行病学,诊断,治疗,疾病的管理,以及控制和预防措施,都包括在这篇文献综述中。