Features of consequences of local radiation injuries of varying severity

Abstract

Relevance. The active development of nuclear and radiation technologies and, as a result, the significant use of ionizing radiation sources in many spheres of life (national economy, science, technology, medicine, etc.) has led to a significant increase in the group of people in contact with ionizing radiation, and, accordingly, to an increase in the risk of abnormal and emergency situations with an increase in the number of victims of radiation. In the clinic of human radiation pathology, local radiation injuries are much more common than other acute radiation injuries. Intention. To determine rates of long-term radiobiological effects in patients with local radiation injuries of varying severity who underwent inpatient treatment in the Clinic of the State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. Methodology. Rates of the consequences of local radiation lesions of varying severity were assessed based on the medical records of 146 patients who were affected by radiation accidents from 1950 to 2013 and underwent inpatient treatment in the Clinic of the State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency during the aftermath. Results and Discussion. Rates of long-term consequences were assessed depending on severity, location and size of local radiation injuries. Degrees of severity determine typical “clinical portraits” of the radiobiological consequences of local radiation injuries. Conclusion. Information about specific rates of long-term consequences of local radiation injuries can be used by healthcare professionals who care of patients affected by radiation accidents when determining adequate treatment and rehabilitation tactics for maximum preservation of working capacity in the period of consequences.