Über den Einbau von intraduodenal appliziertem 14C/32P-Polyen-Phosphatidylcholin in die Leber von Ratten und seine Ausscheidung durch die Galle / Studies on the Incorporation of an Intraduodenal Applied 14C/32P-Polyen-Phospha-tidylcholine into the Liver of Rats and its Excretion in the Bile

Abstract

The incorporation of 14C- (fatty acid-) /32P-phosphatidylcholine containing high amounts of linoleic acid into rat liver and bile was studied. After injection into the intestine, 3.5% of the lipid was incorporated into the liver and 0.2% into the bile. Upon the injection into the portal vein, the corresponding values were 20% and 1 percent. The results show that about 20% of the phospholipid injected into the intestine was absorbed without splitting. From the 14C/32P-ratio of the bile phospholipid it could be concluded that temporarily the injected phospholipid was excreted from the liver into the bile in intact form.