Effects ofWeChat-based peer supports upon medication adherence in liver transplant recipients

Chineae Journal of Organ Transplantation Pub Date : 2019-08-20 DOI:10.3760/CMA.J.ISSN.0254-1785.2019.08.008

Jia Liu, Jianfei Xie, Lifang Liu, Ying Niu, Y. Ming, Ke Chen

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Abstract

Objective To explore the effects of WeChat-based peer supports upon medication adherence and quality-of-life in liver transplant recipients. Methods A total of 63 patients with liver transplantation were conveniently divided into intervention group (n=32) and control group (n=31) depending upon their different follow-up periods. In control group, routine outpatient health guidance was offered while intervention group received 6-week WeChat-based peer supports. Medication compliance and quality-of-life of two groups were evaluated at Month 3/6/12 post-intervention. Results At Month 3 post-intervention, as compared with control group, only non-punctual medication improved significantly in intervention group (P 0.05). However, inter-group quality-of-life was not statistically significant at Month 3/6/12 post-intervention. Conclusions WeChat-based peer supports may partially improve the immediate compliance of patients with liver transplantation. However, long-term outcomes and effects on quality-of-life are worth further researches. Key words: Liver transplantation; Medication; Adherence; WeChat; Peer supports; Quality of life

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微信同伴支持对肝移植受者药物依从性的影响

目的探讨微信同伴支持对肝移植受者药物依从性和生活质量的影响。方法63例肝移植患者根据随访时间不同分为干预组(n=32)和对照组(n=31)。对照组给予常规门诊健康指导，干预组给予为期6周的微信同伴支持。于干预后3/6/12个月对两组患者的用药依从性和生活质量进行评估。结果干预后第3个月，与对照组相比，干预组只有不按时用药情况有明显改善(P < 0.05)。然而，干预后3/6/12个月组间生活质量差异无统计学意义。结论微信同伴支持可部分提高肝移植患者的即时依从性。然而，长期结果和对生活质量的影响值得进一步研究。关键词:肝移植;药物治疗;依从性;微信;同伴支持;生活质量

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Chineae Journal of Organ Transplantation

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