Deep Vein Thrombosis Associated With COVID-19

E. Zaboli, R. Ghasemian, M. Abounoori, Mohammad Zahedi, S. Hashemi
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Abstract

The novel coronavirus disease 2019 (COVD-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The immunothrombosis could occur during infectionwith viruses. Deep vein thrombosis (DVT) is a devastating condition that usually involves the lower extremities. The typical course of DVT is associated with an episode of enormous limbswelling and pain. In this case report, we aimed to present one of the COVID-19 possible complications: DVT in a 38 years old man infected with SARS-CoV-2. A 38 years old manpresented with leg pain. He had a dry cough and fatigue suspicious symptoms of COVID-19. For further evaluations, the lung Computed Tomography scan (CT-scan), labratoricalassessments, and doppler sonography of the common femoral vein (CFV) of both legs were done. Also, for investigating the other underlying causes of DVT, abdominopelvic CT-scan andlumbosacral Magnetic Resonance Imaging (MRI) were done. The CT-scan showed GroundGlass Opacity (GGO) view. Labratorical assessment proposed a thrombotic condition. Thedoppler sonography of the CFV of both legs revealed a massive thrombosis in the left CFV suggesting an acute DVT. Abdominopelvic CT-scan and lumbosacral MRI were negativefor other underlying causes of DVT. COVID-19 is associated with the classical syndrome named disseminated intravascular coagulation and the subsequent consumption coagulopathypresented as DVT.
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与COVID-19相关的深静脉血栓形成
新型冠状病毒病2019 (covid -19)是由严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)引起的。感染病毒时可发生免疫血栓形成。深静脉血栓形成(DVT)是一种通常累及下肢的毁灭性疾病。深静脉血栓的典型病程与剧烈的肢体肿胀和疼痛有关。在本病例报告中,我们旨在介绍COVID-19可能的并发症之一:一名感染SARS-CoV-2的38岁男性的DVT。男性,38岁,腿部疼痛。他有干咳和疲劳症状,疑似新冠肺炎。为了进一步评估,进行了肺部计算机断层扫描(ct)、实验室评估和双腿股总静脉(CFV)的多普勒超声检查。此外,为了调查DVT的其他潜在原因,进行了腹部骨盆ct扫描和腰骶核磁共振成像(MRI)。ct扫描显示磨玻璃不透明(GGO)。实验室检查提示血栓形成。双下肢CFV多普勒超声显示左侧CFV大量血栓形成提示急性DVT。腹部骨盆ct扫描和腰骶MRI未发现其他潜在的DVT原因。COVID-19与称为弥散性血管内凝血的经典综合征以及随后的消耗性凝血途径(表现为DVT)有关。
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