NT-proBNP Levels in Relation to Various Grades of Hypertension – An Observational Study

Abstract

The objectives of this study were to compare levels of NT-proBNP in various grades of hypertension, correlate with electrocardiographic criteria of LVH and with diastolic function on echocardiography. This study was conducted on 100 patients attending the cardiology outpatient department of Nizam’s Institute of Medical Sciences, patients satisfying the inclusion criteria were enrolled in this study after taking informed consent. This study includes the patient population with a mean of 54.32 ± 6 years of age. ECG criteria of LVH are more common in patients with Grade 1 (60%) and Grade 2 (89%) hypertension. Patients with higher grades of hypertension have more LV mass which is corresponding to ECG criteria satisfying LVH and more diastolic dysfunction as well as higher NT pro-BNP values.