Right heart catheterisation is a useful technique to diagnose PAHT, differentiate constrictive/restrictive physiology, to monitor vasodilator treatment outcomes in PAHT. Helpful to assess and quantify intracardiac shunts. To assess the hemodynamics and fluid management after surgical procedures, myocardial infarction with complications, cardiac failure, and cardiogenic shock. It is a very useful method for pre cardiac transplant evaluation, to assess cardiac transplant recipients’ surveillance status. Pre and post procedure evaluation of LVAD [left ventricular assist devices].
{"title":"Right Heart Catheterization-Revisited","authors":"J. Cecily Mary Majella, Shibba Chhabra","doi":"10.25259/ijcdw_14_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_14_2023","url":null,"abstract":"Right heart catheterisation is a useful technique to diagnose PAHT, differentiate constrictive/restrictive physiology, to monitor vasodilator treatment outcomes in PAHT. Helpful to assess and quantify intracardiac shunts. To assess the hemodynamics and fluid management after surgical procedures, myocardial infarction with complications, cardiac failure, and cardiogenic shock. It is a very useful method for pre cardiac transplant evaluation, to assess cardiac transplant recipients’ surveillance status. Pre and post procedure evaluation of LVAD [left ventricular assist devices].","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135803445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Non-alcoholic fatty liver disease (NAFLD) is increasing in prevalence during present obesity pandemic. More than 25% of persons globally are believed to have non-alcoholic fatty liver disease. Many reports claim that there is increased risk of atherosclerotic cardiovascular disease (ASCVD) among patients with non-alcoholic fatty liver disease. NAFLD is a silent disease in initial stages but progress to severe hepatic disease and increase cardiovascular morbidity in later stages, so identification and management of NAFLD are of paramount importance in preventive aspect of cardiovascular disease (CVD). Hence, the aim of present study is to assess the risk of CVD in patients with non-alcoholic fatty liver disease in patients with and without diabetes and to evaluate usefulness of non-alcoholic fatty liver disease as risk factor for CVD. Materials and Methods: The present study is single-center observational study and it included 81 patients with non-alcoholic fatty liver disease. Results: In these patients, cardiovascular risk is assessed by ASCVD score, PROCAM score, QRISK 3 score, and atherogenic index of plasma and compared between diabetic and non-diabetic population. The difference has been found between diabetic and non-diabetic in Procom_score, ASCVD_score, and Q-risk_score but not found in AIP_score. Conclusion: The outcome of this study is that there is an increased risk of cardio vascular disease in patients with non-alcoholic fatty liver disease and risk is further increased in patients with coexisting diabetes mellitus and NAFLD.
{"title":"Assessment of Non-Alcoholic Fatty Liver Disease as Risk Factor for Cardiovascular Disease","authors":"D. Mounika Mellemputi, Hemanth Harish","doi":"10.25259/ijcdw_23_2022","DOIUrl":"https://doi.org/10.25259/ijcdw_23_2022","url":null,"abstract":"Objectives: Non-alcoholic fatty liver disease (NAFLD) is increasing in prevalence during present obesity pandemic. More than 25% of persons globally are believed to have non-alcoholic fatty liver disease. Many reports claim that there is increased risk of atherosclerotic cardiovascular disease (ASCVD) among patients with non-alcoholic fatty liver disease. NAFLD is a silent disease in initial stages but progress to severe hepatic disease and increase cardiovascular morbidity in later stages, so identification and management of NAFLD are of paramount importance in preventive aspect of cardiovascular disease (CVD). Hence, the aim of present study is to assess the risk of CVD in patients with non-alcoholic fatty liver disease in patients with and without diabetes and to evaluate usefulness of non-alcoholic fatty liver disease as risk factor for CVD. Materials and Methods: The present study is single-center observational study and it included 81 patients with non-alcoholic fatty liver disease. Results: In these patients, cardiovascular risk is assessed by ASCVD score, PROCAM score, QRISK 3 score, and atherogenic index of plasma and compared between diabetic and non-diabetic population. The difference has been found between diabetic and non-diabetic in Procom_score, ASCVD_score, and Q-risk_score but not found in AIP_score. Conclusion: The outcome of this study is that there is an increased risk of cardio vascular disease in patients with non-alcoholic fatty liver disease and risk is further increased in patients with coexisting diabetes mellitus and NAFLD.","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135536693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The reported incidence of coronary artery disease (CAD) is on the upsurge in middle-aged women of 35–54 years, whereas decreasing in similar aged matched men. The current clinical trial studies have revealed that attention is drawn away from estrogens and shifted toward androgens and sex hormone-binding globulin considered potential mediators of increasing cardiovascular risk in women at midlife. Data evaluating the endocrinological basis for CAD in premenopausal Indian women is infrequent. We aimed to assess the incidence of CAD among premenopausal women undergoing coronary angiography, identify the prevalence of various risk factors for CAD, and compare clinical characteristics and hormonal levels among premenopausal women with and without CAD to elucidate endocrinological explanations for CAD in premenopausal women. Materials and Methods: Ninety-nine consecutive premenopausal women undergoing coronary angiography between January 2014 and January 2017 were enrolled in this single-center and cross-sectional study. The reproductive hormone levels were quantified using commercially available electrochemiluminescence immunoassay. Results: Sixty-six (66.7%) premenopausal women had CAD on coronary angiography. Multivariate linear regression analysis was used.Diabetes mellitus (adjusted odds ratio [AOR] 16.46; P = 0.006 [95% confidence interval, CI: 2.21–122.41]), triglycerides (AOR 1.05; P = 0.002 [95% CI: 1.02–1.10]), progesterone (AOR 0.68; P = 0.015 [95% CI: 0.50–0.93]), and insulin (AOR 0.51; P < 0.0001 [95% CI: 0.38–0.70]) were observed to independently anticipate the development of CAD in premenopausal women. Conclusion: Approximately two-thirds of premenopausal women undergoing coronary angiography are detected to have CAD. Patients having diabetes, high serum triglyceride levels, low progesterone, and low insulin levels are considered in the high-risk category for developing CAD, thereby in premenopausal women providing a hormonal basis for the development of CAD.
{"title":"Relationship between Serum Sex Hormones and Coronary Artery Disease in Premenopausal Women – A Missing Link?","authors":"Ankit Kumar Sahu, Roopali Khanna, Sudeep Kumar, Naveen Garg, Satyendra Tewari, Aditya Kapoor, Pravin K Goel","doi":"10.25259/ijcdw_40_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_40_2023","url":null,"abstract":"Objectives: The reported incidence of coronary artery disease (CAD) is on the upsurge in middle-aged women of 35–54 years, whereas decreasing in similar aged matched men. The current clinical trial studies have revealed that attention is drawn away from estrogens and shifted toward androgens and sex hormone-binding globulin considered potential mediators of increasing cardiovascular risk in women at midlife. Data evaluating the endocrinological basis for CAD in premenopausal Indian women is infrequent. We aimed to assess the incidence of CAD among premenopausal women undergoing coronary angiography, identify the prevalence of various risk factors for CAD, and compare clinical characteristics and hormonal levels among premenopausal women with and without CAD to elucidate endocrinological explanations for CAD in premenopausal women. Materials and Methods: Ninety-nine consecutive premenopausal women undergoing coronary angiography between January 2014 and January 2017 were enrolled in this single-center and cross-sectional study. The reproductive hormone levels were quantified using commercially available electrochemiluminescence immunoassay. Results: Sixty-six (66.7%) premenopausal women had CAD on coronary angiography. Multivariate linear regression analysis was used.Diabetes mellitus (adjusted odds ratio [AOR] 16.46; P = 0.006 [95% confidence interval, CI: 2.21–122.41]), triglycerides (AOR 1.05; P = 0.002 [95% CI: 1.02–1.10]), progesterone (AOR 0.68; P = 0.015 [95% CI: 0.50–0.93]), and insulin (AOR 0.51; P < 0.0001 [95% CI: 0.38–0.70]) were observed to independently anticipate the development of CAD in premenopausal women. Conclusion: Approximately two-thirds of premenopausal women undergoing coronary angiography are detected to have CAD. Patients having diabetes, high serum triglyceride levels, low progesterone, and low insulin levels are considered in the high-risk category for developing CAD, thereby in premenopausal women providing a hormonal basis for the development of CAD.","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135980753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Satpathy, Trinath Kumar Mishra, Subhasish Singh
Atrial fibrillation (AF) is the most common arrhythmia encountered, especially in elderly. AF leads to fivefold risk of stroke. However, there is a no temporal association found when we compare the onset of AF and stroke suggesting that the presence of AF is not mandatory for stroke occurrence. This has led to concept of atrial myopathy suggesting that a diseased atrium can provoke stroke without AF. Atrial interstitial fibrosis, inflammation, and extracellular matrix deposition can initiate and perpetuate atrial myopathy leading to stasis of blood flowing through the atria and may lead to stroke without intervening AF. AF may be just a marker of atrial myopathy. The present paper reviews the emerging concept of atrial myopathy, its pathogenesis, precursors, and diagnosis.
{"title":"Unraveling Atrial Myopathy","authors":"C. Satpathy, Trinath Kumar Mishra, Subhasish Singh","doi":"10.25259/ijcdw_42_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_42_2023","url":null,"abstract":"Atrial fibrillation (AF) is the most common arrhythmia encountered, especially in elderly. AF leads to fivefold risk of stroke. However, there is a no temporal association found when we compare the onset of AF and stroke suggesting that the presence of AF is not mandatory for stroke occurrence. This has led to concept of atrial myopathy suggesting that a diseased atrium can provoke stroke without AF. Atrial interstitial fibrosis, inflammation, and extracellular matrix deposition can initiate and perpetuate atrial myopathy leading to stasis of blood flowing through the atria and may lead to stroke without intervening AF. AF may be just a marker of atrial myopathy. The present paper reviews the emerging concept of atrial myopathy, its pathogenesis, precursors, and diagnosis.","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84249683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jagadeesh Chandra Bose Yannam, B. Mannuva, Sireesha Konda
Infective endocarditis (IE) is a rare life-threatening infection in pregnancy and postpartum period. In 90% of cases, right-sided IE involves the tricuspid valve. This case report illustrates acute IE with native tricuspid valve vegetation with septic pulmonary embolization in immediate postpartum period.
{"title":"A Rare Case of Postpartum Native Tricuspid Valve Infective Endocarditis with Septic Pulmonary Embolization","authors":"Jagadeesh Chandra Bose Yannam, B. Mannuva, Sireesha Konda","doi":"10.25259/ijcdw_41_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_41_2023","url":null,"abstract":"Infective endocarditis (IE) is a rare life-threatening infection in pregnancy and postpartum period. In 90% of cases, right-sided IE involves the tricuspid valve. This case report illustrates acute IE with native tricuspid valve vegetation with septic pulmonary embolization in immediate postpartum period.","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74613884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Chhabra, Shaina Kamboj, Pranjl Sharma, Suraj Luthra, Mamta Goyal, Anshuman Gupta, Akash Batta, Gautam Singal, Abhishek Goyal, R. Tandon, Vivek Gupta, N. Aslam, B. Mohan, G. Wander
In a tertiary care hospital in Northern India, we examined the demographic, biochemical, and clinical risk factors related to gender differences in COVID-19 patients who were hospitalized. The study was carried out in a hospital with tertiary care. In this retrospective comparative observational study the data was collected from march 2020 to end of COVID pandemic. Analyses were done on the n = 1068 individuals who were hospitalized during the study period. There were 1068 individuals evaluated in the trial, with a male-to-female ratio of 2.3:1. Males and females had similar mean ages (55.84 vs. 55.44 years). Difference was found to be statistically significant in asthmatic boys and females (P = 0.01). In our study, a novel severity score (NSS) was utilized to forecast inpatient mortality in COVID-19 patients. NSS scores were higher for men (2.95) than for women (2.65), with P = 006. Under the categories “Expired,” “discharged against medical advice (DAMA),” and “Discharged,” all the criteria that have been previously analyzed were compared. Based on the number of comorbidities, there was a clear, significant difference between patients who were discharged, expired, and under DAMA, with a P = 0.001. Majority of patients with comorbidities that most frequently impacted the cardiovascular and respiratory outcomes. Studies conducted globally found that men experienced a higher rate of mortality. Our study also indicates that when the number of comorbidities rises, the death rate rises. Therefore, individuals with a larger number of comorbidities, such as hypertension, diabetes, coronary artery disease, and peripheral vascular disease, should exercise particular vigilance.
{"title":"Gender Specific Difference and Clinical Spectrum of COVID-19 Patients Admitted in Tertiary Care Hospital of Northern India","authors":"S. Chhabra, Shaina Kamboj, Pranjl Sharma, Suraj Luthra, Mamta Goyal, Anshuman Gupta, Akash Batta, Gautam Singal, Abhishek Goyal, R. Tandon, Vivek Gupta, N. Aslam, B. Mohan, G. Wander","doi":"10.25259/ijcdw_16_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_16_2023","url":null,"abstract":"\u0000\u0000In a tertiary care hospital in Northern India, we examined the demographic, biochemical, and clinical risk factors related to gender differences in COVID-19 patients who were hospitalized.\u0000\u0000\u0000\u0000The study was carried out in a hospital with tertiary care. In this retrospective comparative observational study the data was collected from march 2020 to end of COVID pandemic. Analyses were done on the n = 1068 individuals who were hospitalized during the study period.\u0000\u0000\u0000\u0000There were 1068 individuals evaluated in the trial, with a male-to-female ratio of 2.3:1. Males and females had similar mean ages (55.84 vs. 55.44 years). Difference was found to be statistically significant in asthmatic boys and females (P = 0.01). In our study, a novel severity score (NSS) was utilized to forecast inpatient mortality in COVID-19 patients. NSS scores were higher for men (2.95) than for women (2.65), with P = 006. Under the categories “Expired,” “discharged against medical advice (DAMA),” and “Discharged,” all the criteria that have been previously analyzed were compared. Based on the number of comorbidities, there was a clear, significant difference between patients who were discharged, expired, and under DAMA, with a P = 0.001. Majority of patients with comorbidities that most frequently impacted the cardiovascular and respiratory outcomes.\u0000\u0000\u0000\u0000Studies conducted globally found that men experienced a higher rate of mortality. Our study also indicates that when the number of comorbidities rises, the death rate rises. Therefore, individuals with a larger number of comorbidities, such as hypertension, diabetes, coronary artery disease, and peripheral vascular disease, should exercise particular vigilance.\u0000","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75087528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Saga of Toil and Consistency","authors":"S. Chhabra","doi":"10.25259/ijcdw_45_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_45_2023","url":null,"abstract":"","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76893714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health-care providers are expected to deliver quality patient care cost-effectively, especially in developing countries. Medical devices labeled “single use only” should ideally not be reused but, can be considered for reuse due to their higher cost. Stringently regulated reprocessing of the single-use device provides an opportunity to do so along with the potential to have a favorable impact on environmental waste. The aim of this study is to assess the acceptance of doctors toward the practice of reusing cardiac disposables in coronary angioplasty. An open-ended and self-designed questionnaire was prepared and was standardized by a panel of cardiologists to assess doctors’ acceptance toward reusing cardiac disposable in coronary angioplasty. The cardiologists were interviewed individually, and the responses were analyzed. The cardiologists were aware that the angioplasty disposables were being reused. The majority were satisfied with the sterilization of disposables and were of the opinion that it was safe for the patients. Cardiac catheters were reused 5–6 times while the balloons were reused 3–4 times. An increase in procedure time of 10–15 min was observed in 30% of patients. There was an increase, in contrast, volume of about 40–50 mL with reused cardiac catheters and balloons which was observed in 15% of patients. Defect in the physical integrity of the catheter, that is, tip abrasion/microfracture was observed in 1% of patients. Deflation dysfunction of the balloon during the procedure was observed in 2% of patients, while breakage of the balloon from the shaft and entanglement of the balloon was observed in 1% of patients. Balloon rupture during angioplasty was observed in 8% of patients. Around 1.5% of patients undergoing angioplasty with reused disposables presented with infections. Thrombosis was observed in 3% of patients with reused disposables, and it was the most common adverse event post-angioplasty. There were cases where the patients were sent for emergency surgery/coronary artery bypass graft surgery due to balloon entanglement and about 0.1% of patients were found to have such a complication. Cardiac disposables can be safely reused by health-care professionals, especially in developing nations due to their budget constraints, provided it is reused no more than 3–5 times and efficient methods of sterilization are observed.
{"title":"A Study to Assess the Acceptance of Doctors toward the Practice of Reusing of Cardiac Disposables in Coronary Angioplasty in a Tertiary Care Hospital","authors":"Pushpi Rani, Humera Irshad, Sajad Rashid, Satyanarayana Nimma","doi":"10.25259/ijcdw_30_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_30_2023","url":null,"abstract":"\u0000\u0000Health-care providers are expected to deliver quality patient care cost-effectively, especially in developing countries. Medical devices labeled “single use only” should ideally not be reused but, can be considered for reuse due to their higher cost. Stringently regulated reprocessing of the single-use device provides an opportunity to do so along with the potential to have a favorable impact on environmental waste. The aim of this study is to assess the acceptance of doctors toward the practice of reusing cardiac disposables in coronary angioplasty.\u0000\u0000\u0000\u0000An open-ended and self-designed questionnaire was prepared and was standardized by a panel of cardiologists to assess doctors’ acceptance toward reusing cardiac disposable in coronary angioplasty. The cardiologists were interviewed individually, and the responses were analyzed.\u0000\u0000\u0000\u0000The cardiologists were aware that the angioplasty disposables were being reused. The majority were satisfied with the sterilization of disposables and were of the opinion that it was safe for the patients. Cardiac catheters were reused 5–6 times while the balloons were reused 3–4 times. An increase in procedure time of 10–15 min was observed in 30% of patients. There was an increase, in contrast, volume of about 40–50 mL with reused cardiac catheters and balloons which was observed in 15% of patients. Defect in the physical integrity of the catheter, that is, tip abrasion/microfracture was observed in 1% of patients. Deflation dysfunction of the balloon during the procedure was observed in 2% of patients, while breakage of the balloon from the shaft and entanglement of the balloon was observed in 1% of patients. Balloon rupture during angioplasty was observed in 8% of patients. Around 1.5% of patients undergoing angioplasty with reused disposables presented with infections. Thrombosis was observed in 3% of patients with reused disposables, and it was the most common adverse event post-angioplasty. There were cases where the patients were sent for emergency surgery/coronary artery bypass graft surgery due to balloon entanglement and about 0.1% of patients were found to have such a complication.\u0000\u0000\u0000\u0000Cardiac disposables can be safely reused by health-care professionals, especially in developing nations due to their budget constraints, provided it is reused no more than 3–5 times and efficient methods of sterilization are observed.\u0000","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80873068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Challenges of Journal Indexing and the Significance of the Quality Peer Review Process","authors":"Sunny Duttagupta","doi":"10.25259/ijcdw_43_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_43_2023","url":null,"abstract":"","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72664545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
With an incidence of 4.1 for women and 6.4 for men/1000 person-years, cardiovascular disease is the primary cause of morbidity and mortality for both men and women worldwide.[1] In asymptomatic patients, subclinical atherosclerosis has been detected utilising several non-invasive methods, such as computed tomography (CT) coronary angiography and Neck Vessel Doppler (NVD) to test coronary calcification. The goal of the present study was to assess the role of NVD in correlation with coronary CT angiography (CCTA) in assessing the coronary artery disease (CAD) burden in diabetic women and men patients. This study was conducted on 30 female patients and 30 male patients aged 40–60 years, who are referred for CCTA for suspected CAD at Nizam’s Institute of Medical Sciences Hospital, Hyderabad. This study was an observational and prospective study of diabetes mellitus patients. All subjects underwent NVD and CCTA scan on the same day. Carotid intimal media thickness (CIMT) was considered the largest of the two separate values (left and right CIMT). The analysis examined factors associated with coronary artery calcification defined as a coronary artery calcium (CAC) score >0. The mean age at assessment was 52.6 years in the diabetic male group and 53.7 in the diabetic female group. 63% of the study population was also hypertensive in the male group and 77% of the study population was also hypertensive in the female group. Mean CIMT was 1.01 mm in the diabetic male group and 1.02 mm in the diabetic female group. Twenty-two (73.3%) patients in the diabetic male group had a CAC score >0, of which 4 (18.18%) had severe coronary artery calcification (CAC score >400 Au), 7 (31.81%) had moderate coronary artery calcification (CAC score 100–400 Au), 11 (50%) had mild coronary artery calcification (CAC score 1-99 Au), and 8 out of 30 (26.67%) had no coronary artery calcification (CAC score <0 Au). Twenty (66.67%) patients in the diabetic female group had a CAC score >0, of which 2 (10%) had severe coronary artery calcification (CAC score >400 Au), 7 (35%) had moderate coronary artery calcification (CAC score 100–400 Au), 11 (55%) had mild coronary artery calcification (CAC score 1-99Au) and 10 out of 30 (33.33%) had no coronary artery calcification (CAC score <0 Au). Mean CIMT and carotid plaque were significantly associated with CAC (P = 0.046 and P = 0.026, respectively, in the diabetic male’s group and P = 0.008 and P = 0.011, respectively, in the diabetic female’s group). The significance was more profound in the diabetic female group when compared to the diabetic male group. NVD giving various surrogate parameters such as CIMT and plaque, in correlation with CCTA (CAC score), can play a significant role in assessing the CAD burden in men and women with diabetes and hypertension, thereby helping the clinician to assess the future risk for stroke or myocardial ischemic events to take active interventions.
{"title":"Role of Neck Vessel Doppler in Correlation with Coronary CT Angiography for Assessing Coronary Artery Disease Burden in Diabetic Women and Men","authors":"Sankeerth Kendyala, Jyotsna Yarlagadda","doi":"10.25259/ijcdw_29_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_29_2023","url":null,"abstract":"\u0000\u0000With an incidence of 4.1 for women and 6.4 for men/1000 person-years, cardiovascular disease is the primary cause of morbidity and mortality for both men and women worldwide.[1] In asymptomatic patients, subclinical atherosclerosis has been detected utilising several non-invasive methods, such as computed tomography (CT) coronary angiography and Neck Vessel Doppler (NVD) to test coronary calcification. The goal of the present study was to assess the role of NVD in correlation with coronary CT angiography (CCTA) in assessing the coronary artery disease (CAD) burden in diabetic women and men patients.\u0000\u0000\u0000\u0000This study was conducted on 30 female patients and 30 male patients aged 40–60 years, who are referred for CCTA for suspected CAD at Nizam’s Institute of Medical Sciences Hospital, Hyderabad. This study was an observational and prospective study of diabetes mellitus patients. All subjects underwent NVD and CCTA scan on the same day. Carotid intimal media thickness (CIMT) was considered the largest of the two separate values (left and right CIMT). The analysis examined factors associated with coronary artery calcification defined as a coronary artery calcium (CAC) score >0.\u0000\u0000\u0000\u0000The mean age at assessment was 52.6 years in the diabetic male group and 53.7 in the diabetic female group. 63% of the study population was also hypertensive in the male group and 77% of the study population was also hypertensive in the female group. Mean CIMT was 1.01 mm in the diabetic male group and 1.02 mm in the diabetic female group. Twenty-two (73.3%) patients in the diabetic male group had a CAC score >0, of which 4 (18.18%) had severe coronary artery calcification (CAC score >400 Au), 7 (31.81%) had moderate coronary artery calcification (CAC score 100–400 Au), 11 (50%) had mild coronary artery calcification (CAC score 1-99 Au), and 8 out of 30 (26.67%) had no coronary artery calcification (CAC score <0 Au). Twenty (66.67%) patients in the diabetic female group had a CAC score >0, of which 2 (10%) had severe coronary artery calcification (CAC score >400 Au), 7 (35%) had moderate coronary artery calcification (CAC score 100–400 Au), 11 (55%) had mild coronary artery calcification (CAC score 1-99Au) and 10 out of 30 (33.33%) had no coronary artery calcification (CAC score <0 Au). Mean CIMT and carotid plaque were significantly associated with CAC (P = 0.046 and P = 0.026, respectively, in the diabetic male’s group and P = 0.008 and P = 0.011, respectively, in the diabetic female’s group). The significance was more profound in the diabetic female group when compared to the diabetic male group.\u0000\u0000\u0000\u0000NVD giving various surrogate parameters such as CIMT and plaque, in correlation with CCTA (CAC score), can play a significant role in assessing the CAD burden in men and women with diabetes and hypertension, thereby helping the clinician to assess the future risk for stroke or myocardial ischemic events to take active interventions.\u0000","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84386211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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