Comparative evaluation of antidiabetic activity of Rosmarinus officinalis L. and Chamomile recutita in streptozotocin induced diabetic rats

Abstract

Herbal formulations are getting more importance in the treatment of diabetes, cancer and hepatic disorder because of the hazardous adverse effects of the current therapy. Especially diabetes can be controlled by Allopathic medicine as well as Herbal medicine. A comparison was made between the antidiabetic activities of water extracts of leaves of Rosmarinus Officinalist and Chamomile recutitain Streptozotocin- induced diabetic rats. Serum Fasting blood glucose and other biochemical parameters such as total protein; carbohydrate hydrolyzing enzyme; α – amylase, total antioxidant capacity, liversteoteosis; total cholesterol, Triacylglycerol, were determined at the dose 200 mg/kg body weight for 21 days. There is a significant increase decrease in serum fasting blood glucose (p<0.001) , increase in body weight and improvement in the other biochemical parameters with treatment of herbal formulations which altered in diabetic rats There was a significant decrease in serum glucose level (p<0.001), increase in body weight and changes in normal cells was observed with treatment of the above mentioned extracts which altered in diabetic rats as compared to the control rats standard.