Hubungan Proteinuria Dengan Jumlah Trombosit pada Pasien Infeksi Dengue

Acivrida Mega Charisma, Elis Anita Farida, Farida Anwari
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Abstract

Dengue Hemorrhagic Fever is a viral infectious disease that often causes high morbidity and mortality in Indonesia every year. Platelet count is one of the parameters that can be used as an indication in the diagnosis of this disease. In its development, severe dengue infection often causes proteinuria because there are no abnormalities in plasma, this condition will continue as the severity of the disease increases. This study aims to find out whether there is a relationship between thrombocytopenia and the incidence of proteinuria in dengue infection. This type of research is a retrospective analytic with a cross-sectional design, the data were taken from medical records at the Vita Medika Clinic laboratory in March – June 2020, including data on examination of thrombosis and examination of proteinuria in dengue patients. Data were analyzed by Spearman correlation test. The results of the study showed that there was a relationship between the number of platelets and the incidence of proteinuria in dengue infection with a value of p=0.002 (p<0.05). This is indicated by the mean, median, maximum and minimal platelet counts in respondents with proteinuria which were lower than respondents without proteinuria.
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蛋白质与登革热感染患者血小板数量的关系
登革出血热是一种病毒性传染病,每年在印度尼西亚经常造成高发病率和死亡率。血小板计数是可用作该病诊断指征的参数之一。在其发展过程中,严重的登革热感染通常会引起蛋白尿,因为血浆中没有异常,这种情况会随着疾病严重程度的增加而持续。本研究旨在探讨登革热感染中血小板减少症与蛋白尿发生率之间是否存在关系。这类研究是一项采用横断面设计的回顾性分析,数据取自2020年3月至6月Vita Medika诊所实验室的医疗记录,包括登革热患者血栓形成检查和蛋白尿检查的数据。数据分析采用Spearman相关检验。研究结果显示,登革热感染患者血小板数量与蛋白尿发生率之间存在相关性,p=0.002 (p<0.05)。这是通过蛋白尿应答者血小板计数的平均值、中位数、最大值和最小值来表明的,这些血小板计数低于无蛋白尿应答者。
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