Diagnosis and treatment of patients with acute and chronic sinusitis using data from studies of physicochemical parameters of nasal secretions

Abstract

Research and analysis of the physicochemical parameters of nasal secretions obtained in the production of the nasal tract are important in the treatment of various diseases. The influence of these parameters on the effective use of drugs is also essential. The acidity of the medium (pH), the density (ρ), and the viscosity (η) of the medium were determined and the specific electrical conductivity (χ) was changed. The selected physicochemical parameters must provide certain values (varying within narrow limits) for the human body. Significant changes in the nature of these indicators are observed in various misconceptions. Based on the above aspects, it can be concluded that it is of great importance to study these parameters. Samples of nasal secretions were taken from people at different stages of their illness (at diagnosis, in the treatment process and after its completion). Samples from individuals with chronic and acute sinusitis were tested. Based on the obtained data, for the acidity of the medium, density, viscosity, and specific electrical conductivity, it could be concluded that all patients benefitted from nasal saline irrigation. After the therapy, the general parameters under study, reach values close to the physicochemical parameters. The results can be used as proper drug treatment or for improving the current drug studies.