Curious Case of Dimethoate Poisoning with Early Onset Intermediate Syndrome, Cardiotoxicity and Hypothermia: A Case Report

M. Sasikumar, R. Gunaseelan, Anuusha Ss, R. Ajithkumar, S. ManuAyyan, N. Balamurugan
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Abstract

Introduction: Organophosphorus (OP) poisoning is one of the major public health concerns which accounts for about 30% suicide annually in India. Despite precautionary measures, intentional and occupational suicidal rates are higher in areas where OP is used. Though the toxidrome based approach is based on OP action on muscarinic and nicotinic receptors, it still can present in atypical ways too. Here, we describe a 37 years old male who presented with symptoms co-relating with Guillain-Barre syndrome but with discordant clinical signs. Some lacuna in the presenting symptoms prompted us to consider organophosphorus poisoning based on toxidrome which was further confirmed with plasma cholinesterase tox screen levels. Our case report highlights the importance of having a high index of suspicion for poisoning, if the clinical features are discordant with clinical history.
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乐果中毒合并早发性中间综合征、心脏毒性和体温过低一例报告
有机磷(OP)中毒是主要的公共卫生问题之一,每年约有30%的印度人自杀。尽管采取了预防措施,但在使用OP的地区,故意和职业自杀率较高。虽然基于毒素的方法是基于OP对毒蕈碱和烟碱受体的作用,但它也可以以非典型的方式出现。在这里,我们描述了一位37岁的男性,他表现出与格林-巴利综合征相关的症状,但临床症状不一致。在表现症状上的一些空白提示我们考虑有机磷中毒,基于中毒,并进一步证实了血浆胆碱酯酶毒素筛查水平。我们的病例报告强调,如果临床特征与临床病史不一致,高度怀疑中毒的重要性。
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