Antioxidant and antibacterial properties of a lichen species Diploschistes scruposus (Schreb.) Norman

B. Sökmen, Sinem Aydın, K. Kınalıoğlu
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引用次数: 8

Abstract

Bu calismada, Diploschistes scruposus (Schreb.) Norman (Graphidaceae) likeninin antibakteriyal ve antioksidan ozellikleri arastirilmistir. D. scruposus likeninin etanol ekstresinin antioksidan aktivitesi bes farkli metodla calisilmistir: DPPH (2,2-difenil-1-pikrilhidrazil) radikal supurme aktivitesi, ABTS.+ (2,2'-azino-bis (3etilbenzotiyazolin-6-sulfonik asit) radikali supurme aktivitesi, indirgeme gucu ve toplam fenolik iceriginin belirlenmesi. Test ekstresinin degisik antioksidan aktiviteleri bilinen antioksidanlarla kiyaslanmistir. Liken ekstresinin %50 inhibisyon konsantrasyon degerleri (IC50), DPPH radikali supurme aktivitesi icin 54.37±0.71; ABTS.+ radikali supurme aktivitesi icin 45.45±0.80 olarak gozlenmistir. D. scruposus etanol ekstresinin 1 mg’inda 161.4±0.01 µg/mL gallik asit esdegeri toplam fenolik bilesikleri bulunmaktadir. Liken ekstresinin antibakteriyal aktivitesi agar kuyu difuzyon yontemine gore belirlenmistir. Maksimum antibakteriyal aktivite Bacillus subtilis’e, en dusuk antibakteriyal aktivite ise Escherichia coli’ye karsi gozlenmistir. Bu calisma, D. scruposus likeninin dogal antioksidan ve antibakteriyal kaynagi olarak kullanilabilecegini gostermistir
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