Inhibition of Garlic Ethanol Extracts (Allium Sativum L.) as a Solvent in Alginate Impression Materials in the Growth of Candida Albicans

Abstract

Alginate is an impression material currently used in dentistry because it has numerous advantages. However, alginate will come into direct contact with blood, saliva, and plaque in its use. Hence, it has the potential to contain pathogenic micro-organisms. One of the micro-organisms that can be pathogenic is Candida Albicans. It can infect the oral cavity and cause candidiasis. Therefore, it is necessary to inhibit Candida Albicans’ growth in the form of a natural ingredient from garlic (Allium sativum L.). Garlic (Allium sativum L.) has benefits as an antifungal since it has an active ingredient, namely allicin. The objective is examining the effect of garlic (Allium sativum L.) ethanol extract as a solvent in alginate impression materials on the growth inhibition of Candida Albicans. The research method was disc diffusion with alginate manipulation using a solvent in distilled water and with ethanol extract of garlic concentrations of 10%, 20%, 40%, and 80%. After that, the clear zone around the disc was measured with a caliper. One-way ANOVA test results indicated that the value was p=0.000 (p<0.05). It means that there were significant differences in the entire treatment group. The results of the Post Hoc LSD test showed that there were significant differences among the sample groups. Therefore, the ethanol extract of garlic (Allium sativum L.) as a solvent in the alginate impression material has an effect on the growth inhibition of Candida Albicans (in vitro).