The relation between vitamin D insufficiency and thyroid hormones in Iraqi women living in Al-Khalidiya, Anbar Province

Abstract

Background: Vitamin D insufficiency is a worldwide issue in all age groups. It wasdiscovered that vitamin D insufficiency is linked to autoimmune disorders such as Irritablebowel illness, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, andrheumatoid arthritis. Vitamin D is also connected to the development of thyroid autoimmunedisease and plays an important role in endocrinopathies including type 1 and type 2 diabetes,adrenal diseases, and polycystic ovarian syndrome.Materials and methods: 100 samples were collected for women from Al-Khalidiya city inAnbar province (50 samples likely to have thyroid problems, 50 healthy samples). The levelsof vitamin D and thyroid hormones were measured using A Minividus system (whichcombines a two-step enzyme sands assay with an ELFA, or End Fluorescent DetectionMethod).Results: The current findings revealed that there are significant variations in vitamin D andT4 levels between patients and healthy controls ( P-value 0.05). There is also a positiveassociation between vitamin D levels and T4 (r = 0.378, P-value = 0.007), as well as anegative correlation between vitamin D levels and TSH (r = -0.373, P-value = 0.008).Conclusion: According to our result, Individuals with hypothyroidism in Alkhaldia have avitamin D3 deficiency. In addition, blood vitamin D levels show a positive correlation with T4and a negative correlation with TSH levels. To avoid developing osteoporosis ifhypothyroidism persists, all hypothyroid Iraqi patients should be checked for Vitamin Ddeficiency.