An Overview on Estimation of Lacidipine from Bulk and Formulation

N. Dighe, Mayur Bhosale, Pallavi B. Gaikwad
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Abstract

Lacidipine is a calcium channel blocker used in treatment of cardiac arrhythmia. Several methods had been reported for the estimation of lacidipine from bulk and formulations. Here in this an attempt is made to summarize the different methods used along with their specifications. Every method reported for the analysis had its own advantages over the other methods. As per the industrial scalability HPLC is the most useful and effective method for the estimation of Lacidipine from bulk and formulations.
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拉西地平原料药和制剂评价综述
拉西地平是一种用于治疗心律失常的钙通道阻滞剂。已报道了几种从原料药和制剂中估计拉西地平的方法。在本文中,我们试图总结使用的不同方法及其规范。报告分析的每种方法都有其自身优于其他方法的优点。根据工业可扩展性,高效液相色谱法是测定拉西地平原料药和制剂中含量的最有效方法。
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