Antibiotics’ Prescribing and Pharmacovigilance Attitudes among Pediatricians and Pediatric Residents in Cyprus

M. Geitona, A. Toska, D. Latsou, M. Saridi, A. Evripidou, I. Evripidou
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引用次数: 3

Abstract

Background: The inappropriate, irrational use or misuse of antibiotics is observed in all health systems and in all patients’ groups worldwide, especially for children, where antibiotics continue to be the drugs most commonly prescribed. Methods: A cross-sectional study was conducted in all public pediatric clinics in the Republic of Cyprus, from April to May 2015. A questionnaire was distributed to pediatricians in order to identify the antibiotic prescription practices in common childhood diseases and attitudes towards Pharmacovigilance. The SPSS 19.0 was used for the statistical analysis. In total 42 pediatricians and pediatric residents filled out the questionnaire. Results: A significant percentage of the respondents administered empirical therapy for possible group A streptococcus infection (59.5%), they implemented the “watchful waiting” tactic in acute otitis media (66.7%), whereas 11.9% of them administered antibiotics for the prevention of secondary respiratory tract infections. The majority of physicians did not feel diagnostic uncertainty leading to antibiotics prescribing (90.2%) and their prescribing habits were not influenced by parental demand (80.5%). Although 23.1% of physicians observed often/very often Adverse Drug Reactions (ADRs) after antibiotic administration during their clinical practice, however, 47.6% of the pediatricians declared that they did not report them. Conclusion: Health professionals’ continuing education on the use of therapeutic guidelines and protocols and the development of Pharmacovigilance programs could significantly contribute to the avoidance of the misuse of antibiotics in hospital care as well as to health professionals’ awareness on rational prescribing.
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塞浦路斯儿科医生和儿科居民的抗生素处方和药物警戒态度
背景:全世界所有卫生系统和所有患者群体中都存在不适当、不合理使用或滥用抗生素的情况,特别是儿童,抗生素仍然是最常用的处方药物。方法:2015年4月至5月在塞浦路斯共和国所有公立儿科诊所进行横断面研究。向儿科医生分发了一份问卷,以确定常见儿童疾病的抗生素处方做法和对药物警戒的态度。采用SPSS 19.0软件进行统计分析。共有42名儿科医生和儿科住院医师填写了问卷。结果:对可能存在的A组链球菌感染采取经验治疗的比例显著(59.5%),对急性中耳炎采取“观察等待”策略的比例显著(66.7%),对继发性呼吸道感染采取抗生素预防的比例显著(11.9%)。绝大多数医生(90.2%)没有诊断不确定性导致抗生素处方,其处方习惯不受父母需求的影响(80.5%)。尽管23.1%的医生在临床实践中观察到抗生素使用后经常/非常经常的药物不良反应(adr),但47.6%的儿科医生声称他们没有报告这些不良反应。结论:卫生专业人员继续接受治疗指南和方案的使用教育,制定药物警戒计划,有助于避免医院护理中抗生素的滥用,提高卫生专业人员合理开处方的意识。
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