Conductive Liquid Bandage Based on Nitrocellulose and Ag Particles for Wound Isolation and Evaluation

Yufeng Chen, Tongren Yang, Junshi Li, Yuanyu Huang, Zhihong Li
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Abstract

Inspired by the commercial liquid bandage for first-aid treatment of wounds, we proposed a kind of Ag-particle-doped liquid bandage (AgP@LB), which can directly form a conductive layer on a wound for simultaneous isolation and evaluation. Ag particles were doped into collodion solution to realize high conductivity and antibacterial property. Compared to the planner electrode used for wound evaluation, the AgP@LB enables more stable and accurate impedance measurement owing to conformal and flexible contact with skin and wound. To demonstrate this feature, we introduced LCR digital bridge to extract electrical parameters from healthy and injured tissue through skin in order to evaluate the wound state. Our preliminary experimental result indicated significant impedance difference between the wounded skin and healthy one.
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基于硝酸纤维素和银颗粒的导电液体绷带伤口隔离及评价
受商业上用于伤口急救治疗的液体绷带的启发,我们提出了一种掺银粒子的液体绷带(AgP@LB),它可以直接在伤口上形成导电层,同时进行隔离和评估。将银颗粒掺入胶体溶液中,实现了高导电性和抗菌性。与用于伤口评估的规划电极相比,AgP@LB由于与皮肤和伤口的保形和灵活接触,可以实现更稳定和准确的阻抗测量。为了证明这一特征,我们引入了LCR数字桥,通过皮肤从健康和受伤组织中提取电参数,以评估伤口状态。我们的初步实验结果表明,损伤皮肤与健康皮肤的阻抗存在显著差异。
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