Medicinal Effect of Pyridoxine - Magnesium for the Cure of Autism Spectrum Disorder

Hafiza Madiha Jaffar, Sadia Sukhera, S. Batool, Asma Draz, B. Rizwan, Zeenat Islam
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Abstract

Dietary interventions involving the use of magnesium and vitamin B6 supplements are considered the most commonly employed therapeutic approach for autism spectrum disorder  (ASD). However, there is currently a lack of investigation into the medicinal efficacy of vitamin and mineral supplementation in improving ASD symptoms. Nonetheless, several researchers have observed a prevalence of nutritional and metabolic abnormalities among individuals with autism. While there is some evidence suggesting that nutrient and mineral supplementation may enhance these fundamental physiological processes, further research is necessary to establish their effectiveness. This review aims to explore potential direct and indirect contributions of metabolism to the primary symptoms of autism, as well as provide evidence regarding nutritional deficiencies and metabolic dysfunction. The present review systematically investigates the existing body of evidence regarding the utilization of high-dose vitamin B6-mg supplementation for the therapeutic intervention in individuals, encompassing both pediatric and adult populations, diagnosed with autism spectrum disorder
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吡哆醇镁治疗自闭症谱系障碍的疗效观察
饮食干预包括使用镁和维生素B6补充剂被认为是自闭症谱系障碍(ASD)最常用的治疗方法。然而,目前缺乏关于补充维生素和矿物质对改善ASD症状的疗效的研究。尽管如此,一些研究人员已经观察到自闭症患者普遍存在营养和代谢异常。虽然有一些证据表明,营养和矿物质补充剂可能会增强这些基本的生理过程,但需要进一步的研究来确定其有效性。本综述旨在探讨代谢对自闭症主要症状的潜在直接和间接影响,并为营养缺乏和代谢功能障碍提供证据。本综述系统地调查了现有的关于使用高剂量维生素B6-mg补充剂进行个体治疗干预的证据,包括儿童和成人,诊断为自闭症谱系障碍
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