Whole Genome Sequence Analysis of a Mycobacterium iranicum, a Newly Identified Non-Tuberculosis Mycobacteria, Strain SBH312 Isolated in Sabah, Malaysia

Jaeyres Jani, Kai Ling Chin, Zainal Arifin Mustapha
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Abstract

In 2021, tuberculosis (TB) incidence partially rebounded but remained 12% lower compared with 2019, in which 10 million new TB cases have been reported worldwide. In Malaysia, 20 – 30% of the total TB cases were reported in Sabah. In this communication, we are reporting the whole genome sequence of Mycobacterium iranicum strain SBH312, isolated from a 49-year-old male suffering from a pulmonary infection. This is the first report of M. iranicum, non-tuberculous mycobacteria infecting humans, from Sabah, state of Malaysia. Phylogenetic analysis showed that the M. iranicum strain SBH312 was closely related to strains from Iran and Peninsular Malaysia.
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马来西亚沙巴地区新发现的非结核分枝杆菌shbh312株伊朗分枝杆菌全基因组序列分析
2021年,结核病发病率出现部分反弹,但与2019年相比仍低12%,2019年全球报告了1000万例新发结核病病例。在马来西亚,报告的结核病例总数的20 - 30%发生在沙巴州。在这篇通讯中,我们报告了从一名49岁男性肺部感染患者中分离出的分枝杆菌(Mycobacterium iranicum)菌株shbh312的全基因组序列。这是马来西亚沙巴州首次报告的感染人类的非结核分枝杆菌伊朗支原体。系统发育分析表明,伊朗支原体菌株shbh312与来自伊朗和马来西亚半岛的菌株亲缘关系密切。
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