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A Cross-Sectional Descriptive Study: Proportion of Authenticity and Complete Product Information of FarmaTag Hologram on Registered Pharmaceutical Products among Selected Mainstream Medicines’ Sellers in the State of Sabah (ProvoS) 横断面描述性研究:沙巴州(ProvoS)部分主流药品销售商注册药品上的 FarmaTag 全息图的真实性和完整产品信息比例
Pub Date : 2024-05-19 DOI: 10.51200/bjms.v18i2.5066
Ahmad Firdaus Shahari, Anitha A/p Uthayakumaran, Zulhilmi Farhan Bin Zulkefli, Muhamad Fikri Bin Bakhtiar, Lavinia Kong Jin Qi
FarmaTag Hologram is a two-dimensional QR code sticker that is required on all registered pharmaceutical products (RPP) in Malaysia. By scanning the QR code, the authenticity and product information of the hologram are displayed. However, FarmaTag holograms with incomplete product information may be susceptible to being misused by manufacturers/distributors/suppliers (MDS) for different pharmaceutical products, unregistered pharmaceutical products, or counterfeit products. In addition to misusing, these callous acts may lead to consumer distrust, doubt, and a lack of confidence in the authenticity of RPP. A cross-sectional descriptive study was conducted among Selected Mainstream Medicines’ Sellers in the State of Sabah between January 2022 and September 2022 to evaluate the proportion of authenticity and complete product information of FarmaTag Hologram on registered pharmaceutical products (RPP) available among selected Mainstream Medicines’ Sellers (MMS) in the state of Sabah. The total sample size was 5048 registered pharmaceutical products. There was no formal sample size calculation performed because this was the first study to explore this topic. All samples being selected from MMS were authentic (100%), which included 31.7% (n = 1600) from private medical clinics, 18.8% (n = 948), from retail pharmacies, and 49.5% (n = 2500) from Non-Pharmacy Drug Stores (NPDS). However, only 268 (5.3%) samples were found to have complete product information. The findings of this study provide preliminary information to relevant authorities on the authenticity and complete product information of FarmaTag Hologram on registered pharmaceutical products among selected MMS in the state of Sabah.
FarmaTag Hologram 是一种二维 QR 码贴纸,马来西亚的所有注册药品 (RPP) 都必须使用该贴纸。通过扫描二维码,全息图的真实性和产品信息就会显示出来。然而,产品信息不完整的 FarmaTag 全息图很容易被制造商/经销商/供应商(MDS)滥用于不同的医药产品、未注册的医药产品或假冒产品。除了滥用之外,这些冷酷无情的行为还可能导致消费者不信任、怀疑和对 RPP 的真实性缺乏信心。2022 年 1 月至 2022 年 9 月期间,在沙巴州选定的主流药品销售商中开展了一项横向描述性研究,以评估沙巴州选定的主流药品销售商(MMS)中注册药品(RPP)上 FarmaTag Hologram 的真实性和完整产品信息的比例。总样本量为 5048 个注册药品。由于这是首次对这一主题进行研究,因此没有进行正式的样本量计算。所有从 MMS 挑选的样本都是真实的(100%),其中包括 31.7%(n = 1600)来自私人医疗诊所,18.8%(n = 948)来自零售药店,49.5%(n = 2500)来自非药房药店(NPDS)。然而,只有 268 个样本(5.3%)有完整的产品信息。这项研究的结果为有关当局提供了初步信息,说明在沙巴州选定的 MMS 中,注册药品上的 FarmaTag Hologram 的真实性和完整产品信息。
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引用次数: 0
A 20-Year Autopsy Study of Myocardial Bridging Among Sudden Deaths 对猝死者心肌桥接的 20 年尸检研究
Pub Date : 2024-05-19 DOI: 10.51200/bjms.v18i2.5063
Ahmad Shafiie Ahmad Amran, F. Mohd Nor, Mohamed Swarhib Shafee, Nadiawati Abdul Razak
Myocardial bridging (MB) is a condition, where the cardiac muscle overlies the intramyocardial segment of the major epicardial coronary artery. This study aims to analyse the demographics and anatomical characteristics of MB within a pool of 2093 sudden cardiac-related death cases examined at the Forensic Unit of Universiti Kebangsaan Malaysia Medical Centre between 2000 and 2019. In this cross-sectional study, postmortem data collected were gender, racial affiliations, MB anatomical properties, and association with cardiac pathologies entered into the statistical software SPSS version 25 for analysis. The prevalence of MB was 12.9%. It was commoner in males (91.5%). MB was predominant between age 21-40 years old (50.2%). Chinese race showed the highest number of recorded MB cases (24.3%) among local races. MB was mostly found in left anterior descending (LAD) artery (98.2%), with the commonest length of 11-20mm (44.6%), depth of 1-5mm (49.8%), and distance from the ostium of 21-40mm (54.0%). The prevalence of isolated MB (43.2%) was nearly comparable to that of MB with cardiac pathologies (56.8%). MB was mostly associated with atherosclerosis (50.1%) and atheroma formation was mostly proximal to MB (78.3%). MB is a common occurrence and commonly found in the LAD as a single entity. It has a higher preponderance in the male gender among the adult population. In conclusion, the findings not only contribute to a deeper understanding of MB but also hold potential implications for identifying and managing risks related to sudden cardiac-related deaths. It is a pathological condition at a certain length and depth whether it exists as an isolated entity or associated with cardiac pathologies. Atherosclerosis tends to form proximal to MB and might pose a risk for myocardial infarction.
心肌桥接(MB)是一种心肌覆盖主要心外膜冠状动脉心内段的情况。本研究旨在分析2000年至2019年期间马来西亚国民大学医疗中心法医室所检查的2093例心脏相关猝死病例中心肌桥接的人口统计学和解剖学特征。在这项横断面研究中,所收集的尸检数据包括性别、种族归属、甲基溴解剖特性以及与心脏病变的关联,并输入 SPSS 25 版统计软件进行分析。甲基溴的发病率为 12.9%。男性更为常见(91.5%)。MB 主要发生在 21-40 岁之间(50.2%)。在本地人种中,中国人种记录的 MB 病例数最多(24.3%)。MB 大多发生在左前降支(LAD)动脉(98.2%),最常见的长度为 11-20 毫米(44.6%),深度为 1-5 毫米(49.8%),距动脉管腔的距离为 21-40 毫米(54.0%)。孤立型 MB 的发病率(43.2%)与伴有心脏病变的 MB 的发病率(56.8%)几乎相当。MB 大多与动脉粥样硬化有关(50.1%),而粥样斑块的形成大多在 MB 近端(78.3%)。MB 是一种常见病,通常作为一个单独的实体出现在左动脉。在成年人群中,男性占多数。总之,这些研究结果不仅有助于加深对 MB 的了解,而且对识别和管理与心脏性猝死相关的风险具有潜在意义。无论是单独存在还是与心脏病变相关联,它都是一种具有一定长度和深度的病理状态。动脉粥样硬化往往在 MB 近端形成,可能会造成心肌梗死的风险。
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引用次数: 0
HTLV-1: Neglected Virus in Southeast Asia for Decades HTLV-1:东南亚被忽视了几十年的病毒
Pub Date : 2024-05-19 DOI: 10.51200/bjms.v18i2.5060
Hidekatsu Iha
There are more than 100 types of human pathogenic viruses, with seven currently known oncogenic viruses (Hulo et al., 2011). Hepatitis B (HBV)/C (HCV) viruses (Mohamed et al., 2023) and human papillomavirus (Wee et al., 2024) are pathogens of public health concern not only in Malaysia but also in many other countries, while Burkitt's lymphoma (Epstein-Barr virus) and Kaposi's sarcoma (Kaposi's sarcoma-associated herpesvirus) pose serious complications for AIDS patients (Carbone et al., 2022).
人类致病病毒有 100 多种,目前已知的致癌病毒有 7 种(Hulo 等人,2011 年)。乙型肝炎(HBV)/丙型肝炎(HCV)病毒(Mohamed 等人,2023 年)和人类乳头瘤病毒(Wee 等人,2024 年)不仅在马来西亚,而且在许多其他国家都是引起公共卫生关注的病原体,而伯基特淋巴瘤(Epstein-Barr 病毒)和卡波西肉瘤(卡波西肉瘤相关疱疹病毒)则给艾滋病患者带来严重的并发症(Carbone 等人,2022 年)。
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引用次数: 0
Emergency Haemorrhoidectomy in Acute Haemorrhoidal Crisis: A Tertiary Centre Experience 急性痔疮危机中的紧急痔切除术:三级中心的经验
Pub Date : 2024-05-19 DOI: 10.51200/bjms.v18i2.5067
Muhd Yusairi Kamarulzaman, Fatin Nur Laily Rosli, Nil Amri Mohamed Kamil, Wan Khamizar Wan Khazim, Michael Pak Kai Wong
Acute haemorrhoidal crisis refers to painful, irreducible prolapsed haemorrhoids. On the best of hand, surgical treatment of acute haemorrhoidal crisis could still risk complications of bleeding and worse, incontinence. Our study aimed to look at the short-term outcomes of emergency excisional haemorrhoidectomy for acute haemorrhoidal crisis at a colorectal centre. This is a retrospective study conducted at a tertiary centre in the northern state of Malaysia from January 2015 to December 2020. The medical record was traced from the medical record unit and the operation theatre list for all patients with surgical treatment for an acute haemorrhoidal crisis. Sociodemographic data and complications rate were collected with 12 months follow-up. There were 51 patients identified from the registry and 29 out of those were male. The median age was 41 (20-82) years old. In addition, 26% (n=13) of the females were pregnant at presentation. Five patients had previous haemorrhoidal procedures performed. The median operating time was 35 (15-143) minutes with the length of hospital stays of 4 (2-10) days. The early complications were seen in 17 patients with bleeding (5.9%) and urinary retention (27%). The 12-month recurrence rate was 7.8% with median Wexner incontinence scores of 0 (0-3). The emergency excisional haemorrhoidectomy in acute haemorrhoidal crisis is safe and effective for immediate symptomatic relief with an acceptable low self-limiting complication rate.
急性痔疮危象指的是疼痛难忍的脱垂痔疮。最好的办法是对急性痔疮危象进行手术治疗,但仍有可能出现出血等并发症,更有甚者会导致大小便失禁。我们的研究旨在了解一家结直肠中心对急性痔疮危象进行紧急切除痔切除术的短期疗效。这是一项回顾性研究,于2015年1月至2020年12月在马来西亚北部州的一家三级中心进行。研究人员从医疗记录部门和手术室名单中追踪了所有因急性痔疮危象而接受手术治疗的患者的医疗记录。在 12 个月的随访中收集了社会人口学数据和并发症发生率。从登记表中确定了 51 名患者,其中 29 人为男性。年龄中位数为 41(20-82)岁。此外,26%(13 人)的女性患者在就诊时已经怀孕。五名患者曾接受过痔疮手术。中位手术时间为 35(15-143)分钟,住院时间为 4(2-10)天。17名患者出现了出血(5.9%)和尿潴留(27%)等早期并发症。12 个月的复发率为 7.8%,Wexner 失禁评分中位数为 0(0-3)分。急性痔疮危象中的紧急痔切除术安全有效,可立即缓解症状,自限性并发症发生率低,可以接受。
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引用次数: 0
Urgency or Emergency – A Report on Hypertensive Crisis with Severe Retinopathy 紧急还是急诊--关于高血压危象伴严重视网膜病变的报告
Pub Date : 2024-05-19 DOI: 10.51200/bjms.v18i2.5068
M. S. E. Shalihin, Mohd Daud Che Yusof
Hypertensive crisis is a common condition encountered in primary care clinics. It may result from uncontrolled hypertension or a known cardiovascular risk disease but may also be the first occurrence of undiagnosed secondary hypertension. However, there is confusion on the classification of whether certain atypical presentations, particularly in young patients without acute symptoms and exact duration of symptoms, are to be considered as hypertensive urgency or emergency. Some abnormal signs, such as proteinuria or retinopathy, could be signs of an existing progression of underlying chronic disease rather than a manifestation of acute hypertensive crisis. Nonetheless, in any situation where the findings have occurred recently without prior follow-up, they should be treated as if they are signs of an acute hypertensive crisis. Bedside clues, such as concomitant anaemia and proteinuria, are valid evidence for the presence of end-stage renal disease (ESRD) causing the hypertensive crisis, even without the features of fluid overload or failure symptoms. We report the case of a young man presented with an acute hypertensive crisis with an isolated one-month history of blurred vision. Despite the initial dilemma, the case was treated as a hypertensive emergency due to the presence of retinopathy and overt proteinuria. The renal profile later confirmed that the patient had ESRD. This case proves that ESRD is still possible even in a young patient without a long medical history or other supporting signs. Making the right decision on the first visit saved the patient’s life.
高血压危象是初级保健诊所常见的一种疾病。它可能由未控制的高血压或已知的心血管风险疾病引起,但也可能是未确诊的继发性高血压的首次出现。然而,对于某些非典型表现,尤其是没有急性症状和确切症状持续时间的年轻患者,是否应将其视为高血压急症或急诊,目前还存在分类上的混乱。一些异常体征,如蛋白尿或视网膜病变,可能是潜在慢性疾病进展的征兆,而不是急性高血压危象的表现。尽管如此,如果这些异常体征是在近期出现的,且事先未进行随访,则应将其视为急性高血压危象的征兆。即使没有液体超负荷或衰竭症状,床旁的线索,如同时出现的贫血和蛋白尿,也是终末期肾病(ESRD)导致高血压危象的有效证据。我们报告了一例年轻男性急性高血压危象患者的病例,该患者仅有一个月的视力模糊病史。尽管起初患者进退两难,但由于存在视网膜病变和明显蛋白尿,该病例被作为高血压急症治疗。后来的肾功能检查证实,患者患有 ESRD。这个病例证明,即使是没有长期病史或其他辅助体征的年轻患者,也有可能患上 ESRD。首次就诊时做出的正确决定挽救了患者的生命。
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引用次数: 0
Exploring the Awareness, Perception, Acceptability and Confidence Level Towards Telerehabilitation among Stroke Patients’ Caregivers in the Federal Territory of Malaysia 探讨马来西亚联邦直辖区中风患者护理人员对远程康复的认识、看法、接受程度和信心水平
Pub Date : 2024-01-31 DOI: 10.51200/bjms.v18i1.3973
Nik Nasihah, Nik Ramli, Amirul Fikri, Khamarul Bahrin, Ayu Puspita, Sari Ainulhakim, Darmini Selvan
Telerehabilitation is the ability to provide distance support, evaluation and intervention to individuals who are undergoing rehabilitation therapy through telecommunication. This study aimed to explore the awareness, acceptability and confidence level towards telerehabilitation among caregivers of cerebral stroke patients in the federal territory of Malaysia. A cross-sectional study was conducted amongst stroke patients’ caregivers from general hospitals in the federal territory of Malaysia. Descriptive statistics were used to analyse the awareness, acceptability and confidence level towards telerehabilitation technology among stroke patients’ caregivers. The correlation between confidence level in using technology devices and their acceptance level of telerehabilitation was assessed by using Spearman correlation analysis. Results showed that 70% of caregivers were aware of the telerehabilitation technology, amongst which 60.5% were willing to use the technology for rehabilitation purposes. Out of all the types of devices, 50% of caregivers demonstrated a high confidence level in using smartphones. However, only 25.7% demonstrated a high confidence level in using video call services for telerehabilitation service. In conclusion, the majority of caregivers in the federal territory of Malaysia demonstrated a positive attitude towards telerehabilitation services for stroke patients.
远程康复是指通过远程通信为正在接受康复治疗的个人提供远程支持、评估和干预的能力。本研究旨在探讨马来西亚联邦地区脑中风患者护理人员对远程康复的认识、接受程度和信心水平。本研究对马来西亚联邦地区综合医院的中风患者护理人员进行了横断面研究。研究采用描述性统计方法分析了中风患者护理人员对远程康复技术的认知度、接受度和信心水平。使用斯皮尔曼相关分析法评估了护理人员使用技术设备的信心水平与他们对远程康复技术接受程度之间的相关性。结果显示,70% 的照护者了解远程康复技术,其中 60.5% 愿意使用该技术进行康复。在所有类型的设备中,50%的护理人员对使用智能手机表现出高度信心。然而,只有 25.7% 的护理人员对使用视频通话服务进行远程康复服务表现出高度信心。总之,马来西亚联邦地区的大多数护理人员对中风患者的远程康复服务持积极态度。
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引用次数: 0
Meguro Parasitological Museum – A Wonderful Experience Full of Surprises 目黑寄生虫博物馆 - 充满惊喜的奇妙体验
Pub Date : 2024-01-31 DOI: 10.51200/bjms.v18i1.4857
Kamruddin Ahmed, Siat Yee Fong
In November 2023, one of us had the opportunity to visit the Meguro Parasitological Museum in Tokyo, Japan. The museum started its journey in 1953 with private funding from Dr Satoru Kamgeai. Now, the museum is a 70-year-old private research facility with its researchers who not only collect parasites of various animals for studies on morphology, taxonomy, distribution of parasites, etc. but also give presentations at academic meetings and publish articles in academic journals. 
2023 年 11 月,我们有幸参观了日本东京的目黑寄生虫博物馆。该博物馆于 1953 年在 Satoru Kamgeai 博士的私人资助下开始运营。现在,该博物馆已成为一家拥有 70 年历史的私人研究机构,其研究人员不仅收集各种动物的寄生虫,对寄生虫的形态、分类、分布等进行研究,还在学术会议上发表演讲,并在学术期刊上发表文章。
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引用次数: 0
Postgraduate Nursing Education in Malaysia and Advanced Nursing Practice: Where Are We and What’s Next? 马来西亚的护理研究生教育和高级护理实践:我们在哪里?
Pub Date : 2024-01-31 DOI: 10.51200/bjms.v18i1.4858
Noor Azizah, Mohd Ali, K. Aung, Hanida Hani, Mohd Mokhtar, Ashikin Atan, Hairanni Mohd Noh, Sarina Ahmad
The nursing profession plays a pivotal and indispensable role in the promotion of public health, disease prevention, and comprehensive care delivery to diverse populations. As in other healthcare-related fields, the continuous development of nursing education assumes paramount importance in addressing the myriad challenges posed by the modern era. This paper presents a thorough examination of the historical origins, current status, and future prospects of postgraduate nursing education in Malaysia, encompassing a thorough exploration of its evolution. Furthermore, the study critically examines the interface between postgraduate nursing education and advanced nursing practice within the healthcare landscape of Malaysia. By analysing these dimensions, this paper contributes to a deeper understanding of the strategic enhancements necessary for further strengthening the nursing profession in the country.
护理专业在促进公共卫生、预防疾病和为不同人群提供全面护理方面发挥着不可或缺的关键作用。与其他医疗保健相关领域一样,护理教育的持续发展对于应对现代社会带来的无数挑战至关重要。本文对马来西亚护理研究生教育的历史渊源、现状和未来前景进行了深入研究,包括对其演变过程的全面探索。此外,本研究还批判性地探讨了马来西亚医疗保健领域中护理研究生教育与高级护理实践之间的关系。通过对这些方面的分析,本文有助于加深对进一步加强马来西亚护理专业所需的战略改进的理解。
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引用次数: 0
An Uncommon Aetiology of Native Valve Infective Endocarditis: Corynebacterium glutamicum Infective Endocarditis 一种不常见的原生瓣膜感染性心内膜炎病因:谷氨酸棒状杆菌感染性心内膜炎
Pub Date : 2024-01-31 DOI: 10.51200/bjms.v18i1.3157
C. Siaw, Nor Izzah Binti Mazan, S. Cheo, Q. Low
Corynebacterium glutamicum is a rare cause of infective endocarditis increasingly identified as a pathogen causing significant morbidity and mortality. We report a middle-age female with underlying end-stage renal failure who developed Corynebacterium glutamicum catheter-related bloodstream infection and eventually succumbed. This case highlights the importance of recognizing Corynebacterium as an emerging nosocomial pathogen and early management to improve clinical outcome.
谷氨酸棒状杆菌是感染性心内膜炎的一种罕见病因,越来越多的人将其视为导致严重发病和死亡的病原体。我们报告了一名患有终末期肾衰竭的中年女性,她发生了谷氨酸棒状杆菌导管相关血流感染,最终不治身亡。本病例强调了认识到谷氨酸棒状杆菌是一种新出现的院内病原体并及早处理以改善临床预后的重要性。
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引用次数: 0
Helminth Infestation Causing Anaemia in Pregnancy Attending Primary Care Clinic: A Case Report 在初级保健诊所就诊的孕妇因蠕虫感染导致贫血:病例报告
Pub Date : 2024-01-31 DOI: 10.51200/bjms.v18i1.4223
Yashdev Atri, Roop Kishore, Mohd Shaiful, Ehsan Shalihin
Anaemia in pregnancy is among the commonest medical disorders encountered antenatally. However, the condition has sometimes been overlooked and not corrected accordingly given wrong or unidentified exact causes. Helminth infestation, even though rare generally nowadays, is still an important cause that needs to be ruled out in case of anaemia. We reported a case of an antenatal woman who presented with unresolved anaemia. However, she benefited from the helminth infestation screening and was able to be treated well. Her condition tremendously improved after the eradication of the infection. This case highlighted that anaemia should always include stool for ova and cyst despite no convincing history towards the infection. The symptoms could be mild or even not recognised.
妊娠贫血是产前最常见的疾病之一。然而,由于错误或未找到确切原因,这种情况有时会被忽视,得不到相应的纠正。尽管螺旋虫感染在当今已很少见,但仍是导致贫血的一个重要原因。我们报告了一例产前妇女贫血的病例。然而,她受益于蠕虫感染筛查,并得到了很好的治疗。根除感染后,她的病情大有好转。这个病例突出表明,尽管没有令人信服的感染史,但贫血患者的粪便中仍应含有卵巢和囊肿。症状可能很轻微,甚至无法识别。
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引用次数: 0
期刊
Borneo Journal of Medical Sciences (BJMS)
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