Acute Pipazethate HCl (Selgon, Eipico Egypt, Egypt) Toxicity: Case Report

M. Abdelnaby, Ahmed M. Ibrahim, Muhammad Mahmoud Abdul Haleem
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引用次数: 1

Abstract

Pipazethate HCl is a centrally acting non-narcotic antitussive which is infrequently used nowadays. The toxicity of this drug is rarely reported in the literature. We were encountered with a case of accidental ingestion of Pipazethate HCl in a 3-years-old child presented with neurological symptoms in the form of somnolence, disturbed sensorium, respiratory symptoms in the form of respiratory distress and cardiac dysrhythmias in the form of Torsade de pointes. The patient was managed at a critical care unit using supportive measures for neurological symptoms, shock state and respiratory distress. Arrhythmic complications were managed using magnesium sulphate and maintained on lidocaine infusion. After two days under observation, the child was discharged home safely.
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急性哌乙酯HCl (Selgon, Eipico Egypt, Egypt)毒性:病例报告
盐酸哌唑乙酯是一种中枢作用的非麻醉性止咳药,目前很少使用。这种药物的毒性在文献中很少报道。我们遇到了一个3岁儿童意外摄入盐酸吡嗪酸酯的病例,他出现了以嗜睡、感觉障碍、呼吸窘迫为形式的神经系统症状和以点侧畸形为形式的心律失常。患者在重症监护病房接受治疗,对神经症状、休克状态和呼吸窘迫采取支持性措施。心律失常并发症采用硫酸镁治疗,并输注利多卡因维持。经过两天的观察,孩子安全出院回家。
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