Current evidence for mutations responsible for murine rodent resistance

Istomina Lyudmila Innokentievna, Gevorgyan Irina Sergeevna, Bogdanova Elena Nikolaevna, Andreev Sergey Viktorovich
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Abstract

Modern means of rodent control, mechanism of blood anticoagulants action, emergence of resistance to anticoagulants are considered. Outbreaks of rodent numbers, including those associated with their resistance, force the search for new ways and means to reduce them. The widespread use of acute poisons poses a risk to humans and the environment. In this regard, it is necessary to search for new active substances for deratization agents, the mechanism of action of which would not be associated with the transformation of vitamin K in the body. Keywords: resistance, rodents, anticoagulants.
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目前的证据突变负责小鼠啮齿动物抗性
讨论了现代鼠类控制手段、抗凝血药物作用机制、抗凝血药物耐药性的出现。啮齿动物数量的激增,包括与它们的抵抗力有关的数量,迫使人们寻找新的方法和手段来减少它们。急性毒物的广泛使用对人类和环境构成了风险。因此,有必要寻找新的除鼠剂活性物质,使其作用机制与体内维生素K的转化无关。关键词:耐药性,啮齿动物,抗凝血剂。
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