Development of Piezoelectric Sensors on the Basis of Electrosynthesized Molecularly Imprinted Polymers for β-lactam Antibiotics’ Detection

Nadezhda A. Karaseva, Ekaterina A. Belyaeva, Valentina V. Levkina, Irina G. Soboleva, Tatyana N. Ermolaeva
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引用次数: 6

Abstract

Piezoelectric sensors with the receptor coating on the basis of molecularly imprinted polymers of cefotaxime and penicillin G obtained by the electropolymerization method directly on the surface of the sensor's electrode have been developed. The obtained calibration curves are linear in the range of concentrations (ng·mL-1) 5 – 150 and 10 – 150, the limits of detection are 3.0 and 7.6 (ng·mL-1) for penicillin G and cefotaxime respectively. The developed sensors were tested in the analysis of model solutions of antibiotics, samples of meat and milk. The analysed samples did not reveal exceeding antibiotics.

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基于电合成分子印迹聚合物的β-内酰胺类抗生素检测压电传感器的研制
利用电聚合法制备了头孢噻肟和青霉素G的分子印迹聚合物,在传感器电极表面直接涂覆了受体。在浓度(ng·mL-1) 5 ~ 150和10 ~ 150范围内均呈线性关系,青霉素G和头孢噻肟的检出限分别为3.0和7.6 (ng·mL-1)。开发的传感器在抗生素模型溶液、肉类和牛奶样品的分析中进行了测试。经分析的样本没有发现抗生素超标。
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