Bochao Cheng, Yi Guo, Xijian Chen, Bin Lv, Yi Liao, Haibo Qu, Xiao Hu, Haoxiang Yang, Yajing Meng, Wei Deng, Jiaojian Wang
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引用次数: 0
Abstract
Background: Although postpartum depression (PPD) and non-peripartum major depressive disorder (MDD) occurring within and outside the postpartum period share many clinical characteristics, whether PPD and MDD are the same or not remains controversial.
Methods: The current study was devoted to identify the shared and different neural circuits between PPD and MDD by resting-state functional magnetic resonance imaging data from 77 participants (22 first-episodic drug-naïve MDD, 26 drug-naïve PPD, and 29 healthy controls (HC)).
Results: Both the PPD and MDD groups exhibited higher fractional amplitude of low-frequency fluctuation (fALFF) in left temporal pole relative to the HC group; the MDD group showed specifically increased degree centrality in the right cerebellum while PPD showed specifically decreased fALFF in the left supplementary motor area and posterior middle temporal gyrus (pMTG_L), and specifically decreased functional connectivities between pMTG and precuneus and between left subgeneual anterior cingulate cortex (sgACC_L) and right sgACC. Moreover, sgACC and left thalamus showed abnormal regional homogeneity of functional activities between any pair of HC, MDD, and PPD.
Conclusions: These results provide initial evidence that PPD and MDD have common and distinct neural circuits, which may facilitate understanding the neurophysiological basis and precision treatment for PPD.
期刊介绍：
Asian Ethnology (ISSN 1882–6865) is a double-blind peer-reviewed journal registered as an Open Access Journal with all the contents freely downloadable. Please read the information on our open access and copyright policies. A list of monographs that were published under the journal''s former names, Folklore Studies and Asian Folklore Studies, appear here. Asian Ethnology is dedicated to the promotion of scholarly research on the peoples and cultures of Asia. It began in China as Folklore Studies in 1942 and later moved to Japan where its name was changed to Asian Folklore Studies. It is edited and published at Nanzan University in Nagoya, Japan, with the cooperation of Boston University. Asian Ethnology seeks to deepen understanding and further the pursuit of knowledge about the peoples and cultures of Asia. We wish to facilitate intellectual exchange between Asia and the rest of the world, and particularly welcome submissions from scholars based in Asia. The journal presents formal essays and analyses, research reports, and critical book reviews relating to a wide range of topical categories, including: -narratives, performances, and other forms of cultural representation -popular religious concepts -vernacular approaches to health and healing -local ecological/environmental knowledge -collective memory and uses of the past -cultural transformations in diaspora -transnational flows -material culture -museology -visual culture
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