{"title":"Role of autophagy in male and female fertility","authors":"Chao Liu , Bingbing Wu , Wenwen Liu , Wei Li","doi":"10.1016/j.cophys.2022.100611","DOIUrl":null,"url":null,"abstract":"<div><p>Autophagy is an important cellular homoeostatic process that transports cytoplasmic constituents to lysosomes<span> and participates in various physiological processes. Recent findings have revealed novel functional roles of autophagy in the reproductive process, and dysfunctional autophagy has been reported to be associated with male and female infertility. In this review, we summarise the recent progress regarding autophagy in fertility and discuss important concerns in this field.</span></p></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"30 ","pages":"Article 100611"},"PeriodicalIF":2.5000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Physiology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468867322001298","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
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Abstract
Autophagy is an important cellular homoeostatic process that transports cytoplasmic constituents to lysosomes and participates in various physiological processes. Recent findings have revealed novel functional roles of autophagy in the reproductive process, and dysfunctional autophagy has been reported to be associated with male and female infertility. In this review, we summarise the recent progress regarding autophagy in fertility and discuss important concerns in this field.
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