Analgesic activity of Hydroalcholic extract of Achyranthes aspera leaves on animal model

K. Shukla, Sourabh Jain, Narendra B. Patil, K. Patil, Kalpesh S. Wagh
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Abstract

Achyranthes aspera L. (Family: Amaranthaceae) is widely used as a medicinal plant. The hydroalcholic extract of Achyranthes aspera L. leaves was screened for its analgesic activity. The dose (200 mg/kg) was tested for analgesic activity using hot plate and Tail flick test in albino mice. The hydroalcholic extract of Achyranthes aspera L. leaves showed maximum analgesic activity in hot plate at reaction time 120 min (7.40±0.08) and tail flick method at reaction time 120 min (6.9±0.06). These study suggest that the hydroalcholic extract of Achyranthes aspera L. could be considered as potential analgesic agent.
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牛膝水醇提取物对动物模型的镇痛作用
牛膝草(苋科)是一种广泛使用的药用植物。对牛膝叶水醇提取物进行了镇痛活性筛选。采用热板法和甩尾法测定剂量(200 mg/kg)对白化小鼠的镇痛活性。热板法和甩尾法分别在反应时间120 min(7.40±0.08)和120 min(6.9±0.06)时表现出最大的镇痛活性。提示牛膝水醇提取物可作为一种潜在的镇痛药。
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