Peripheral ossifying fibroma: A series of four cases

Abstract

Peripheral ossifying fibroma (POF) is composed of fibroblastic connective tissue stroma which is associated with the formation of randomly dispersed foci of mineralized products which consists of bone, cementoid-like substance, or dystrophic calcification. The color of the lesion ranges from red to pink and is frequently ulcerated. Either sessile or pedunculated the size is <2 cms. POF shows a striking female predilection occurring mostly between 2nd and 3rd decades of life. It occurs exclusively on gingiva, frequently on maxilla than mandible, around incisors and canines. Adjacent teeth are usually not affected. Microscopically, POF appears as combination of mineralized product and fibrous proliferation. Highly developed bone or cementum is more likely to be present in long-standing lesions. The objectives of this current case series are to discuss the clinical manifestations, and histopathological presentations of four cases of POF, which were on regular follow-up along with a minireview on the same.