S. Bahadoram, M. Mahmoudian-sani, B. Keikhaei, M. Bahadoram, Amar Helalinasab, E. Akade
{"title":"Colchicine; An inflammasome inhibitor and a potential therapy in severe COVID19?","authors":"S. Bahadoram, M. Mahmoudian-sani, B. Keikhaei, M. Bahadoram, Amar Helalinasab, E. Akade","doi":"10.34172/jre.2022.19065","DOIUrl":null,"url":null,"abstract":"policy/practice/research/medical education Inflammatory reactions are among the most adverse complications of COVID-19 patients. These reactions occur generally via inflammasomes. Inflammasomes are regulated by some proteins such as NLRP3. Colchicine is well-known drug which bars inflammasome formation by inhibiting NLRP3. In presented article we propose studying efficacy, adverse effects, and exact mechanism of action of colchicine in COVID-19 patients.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"30 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Renal Endocrinology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/jre.2022.19065","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
policy/practice/research/medical education Inflammatory reactions are among the most adverse complications of COVID-19 patients. These reactions occur generally via inflammasomes. Inflammasomes are regulated by some proteins such as NLRP3. Colchicine is well-known drug which bars inflammasome formation by inhibiting NLRP3. In presented article we propose studying efficacy, adverse effects, and exact mechanism of action of colchicine in COVID-19 patients.
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