Greater Occipital Nerve Block or Suboccipital Intramuscular Injections are effective for management of Postdural Puncture Headache: A placebo-controlled study

Islam A. Shaboob, S. Salman
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Abstract

Background: Postdural puncture headache (PDPH) is not uncommon complication of neuroaxial anesthesia and it affects the mother and the newborn. PDPH may be resistant to conservative management and requires intervention. Objectives: To evaluate the outcomes of bilateral greater occipital nerve block (GONB) and bilateral suboccipital intramuscular injection in a placebo-controlled study for management of PDPH. Patients and methods: 50 patients received bilateral saline injection, 32 patients received suboccipital intramuscular injection and 33 patients received GONB using a mixture of 40 mg lidocaine and 8 mg dexamethasone injection . Pain severity was assessed using the Numeric Rating Scale at baseline and weekly for 4-wks and monthly for 6-m after block, Pain-induced disability was assessed using the Oswestry Pain Disability Questionnaire (OPDQ) score and analgesic requirements were graded at baseline, 1, 3-and 6-m after block. The success rate was defined at the end of 6-m follow-up as the frequency of patients who stopped consumption of analgesia and/or had minimal-to-mild disability with OPDQ score of <20. Results: The success rates were 46.2% depending on number of women had stopped analgesia and 52.3% depending on the OPDQ score and was significantly higher among patients received GONB. Patients' distribution according to satisfaction grade was significantly higher in study groups than control groups with non-significant differences between the study groups. Conclusion: The applied procedures are effective for reducing pain severity, consumption of analgesics and improving disability. GONB provided significantly higher success rate,
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枕大神经阻滞或枕下肌内注射对硬脊膜穿刺后头痛有效:一项安慰剂对照研究
背景:硬脊膜穿刺后头痛(PDPH)是神经轴麻醉的一种常见并发症,可影响产妇和新生儿。PDPH可能抵抗保守治疗,需要干预。目的:评价双侧枕大神经阻滞(GONB)和双侧枕下肌内注射治疗PDPH的安慰剂对照研究结果。患者和方法:50例患者双侧生理盐水注射,32例患者枕下肌内注射,33例患者采用利多卡因+地塞米松注射液8 mg混合的GONB。疼痛严重程度在基线、阻滞后4周每周和阻滞后6 m每月使用数字评定量表进行评估,疼痛引起的残疾使用Oswestry疼痛残疾问卷(OPDQ)评分进行评估,镇痛需求在基线、阻滞后1、3和6 m进行分级。在6 m随访结束时,成功率定义为停止使用镇痛药和/或OPDQ评分<20的患者有轻微至轻度残疾的频率。结果:以停药次数为标准的成功率为46.2%,以OPDQ评分为标准的成功率为52.3%,在接受GONB治疗的患者中成功率明显较高。研究组患者满意度分布明显高于对照组,组间差异无统计学意义。结论:所采用的手术方法对减轻疼痛程度、镇痛药的使用和改善残疾是有效的。GONB的成功率明显更高;
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4 weeks
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