Can Multi-Detector Computed Tomography Classify (MDCT) Non-Compacted Left Ventricle in Coloration to The Genetic Structure?

Abstract

Introduction Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity [1]. The clinical sequelae of these deformities are the syndrome of heart failure, arrhythmias and stroke. Dusek first described the postnatal persistence of spongy myocardium in 1975 pathologically, but Engberding and Bender made the first clinical recognition with two-dimensional (2D) echocardiography in 1984 [2,3]. Three decades later, with only morphologic assessment available and no definitive genetic pathway, isolated left ventricular noncompaction (LVNC) remains a diagnostic and management challenge. In this review, we wish to spot light on how MDCT can visualize the shape and distribution of spongy myocardium clearer than echocardiography.