Functional disability and social participation restriction associated with chronic conditions in middle-aged and older adults

L. Griffith, P. Raina, M. Levasseur, N. Sohel, H. Payette, H. Tuokko, E. R. van den Heuvel, A. Wister, A. Gilsing, Christopher J. Patterson
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引用次数: 68

Abstract

Background We examine the population impact on functional disability and social participation of physical and mental chronic conditions individually and in combination. Methods Cross-sectional, population-based data from community-dwelling people aged 45 years and over living in the 10 Canadian provinces in 2008–2009 were used to estimate the population attributable risk (PAR) for functional disability in basic (ADL) and instrumental (IADL) activities of daily living and social participation restrictions for individual and combinations of chronic conditions, stratified by age and gender, after adjusting for confounding variables. Results Five chronic conditions (arthritis, depression, diabetes, heart disease and eye disease) made the largest contributions to ADL-related and IADL-related functional disability and social participation restrictions, with variation in magnitude and ranking by age and gender. While arthritis was consistently associated with higher PARs across gender and most age groups, depression, alone and in combination with the physical chronic conditions, was associated with ADL and IADL disability as well as social participation restrictions in the younger age groups, especially among women. Compared to women, the combinations of conditions associated with higher PARs in men more often included heart disease and diabetes. Conclusions Our findings suggest that in community-dwelling middle-aged and older adults, the impact of combinations of mental and physical chronic conditions on functional disability and social participation restriction is substantial and differed by gender and age. Recognising the differences in the drivers of PAR by gender and age group will ultimately increase the efficiency of clinical and public health interventions.
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中老年人慢性疾病相关的功能残疾和社会参与限制
我们研究了个体和组合的身心慢性病对功能残疾和社会参与的人口影响。方法采用2008-2009年加拿大10个省45岁及以上社区居民的横断面人口数据,在调整混杂变量后,按年龄和性别分层,估计日常生活基本(ADL)和工具(IADL)活动功能残疾的人口归因风险(PAR),以及个人和慢性病组合的社会参与限制。结果5种慢性疾病(关节炎、抑郁症、糖尿病、心脏病和眼病)对adl相关和adl相关功能残疾和社会参与限制的贡献最大,其程度和排名因年龄和性别而异。尽管在性别和大多数年龄组中,关节炎始终与较高的par相关,但抑郁症,单独或结合身体慢性疾病,与年轻年龄组,特别是女性的ADL和IADL残疾以及社会参与限制有关。与女性相比,男性与较高par相关的疾病组合通常包括心脏病和糖尿病。结论:在社区居住的中老年人中,身心慢性病对功能残疾和社会参与限制的影响是显著的,且因性别和年龄而异。认识到按性别和年龄组划分的PAR驱动因素的差异,最终将提高临床和公共卫生干预措施的效率。
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