Co-infections and co-therapies: treatment of HIV in the presence of hepatitis C and hepatitis B

M. Potter, M. Klein
{"title":"Co-infections and co-therapies: treatment of HIV in the presence of hepatitis C and hepatitis B","authors":"M. Potter, M. Klein","doi":"10.2217/17584310.3.2.189","DOIUrl":null,"url":null,"abstract":"An increasing number of people are chronically infected with HIV and HCV, and/or HBV owing to shared routes of transmission. With the advent of HAART, liver disease secondary to hepatitis co-infections has emerged as a leading cause of morbidity and mortality in HIV-infected persons. There is increasing need to manage dual infection, but treatment is complicated by co-morbidities, overlapping toxicities, drug activities and resistance. A model of treatment that builds on the lessons learned from the treatment of HIV has evolved to maximize success of treating dual infections. This review will address current strategies for the management of HIV in the setting of HCV and HBV co-infection and discuss future treatment directions and challenges.","PeriodicalId":88510,"journal":{"name":"HIV therapy","volume":"40 1","pages":"189-207"},"PeriodicalIF":0.0000,"publicationDate":"2009-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"HIV therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/17584310.3.2.189","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

Abstract

An increasing number of people are chronically infected with HIV and HCV, and/or HBV owing to shared routes of transmission. With the advent of HAART, liver disease secondary to hepatitis co-infections has emerged as a leading cause of morbidity and mortality in HIV-infected persons. There is increasing need to manage dual infection, but treatment is complicated by co-morbidities, overlapping toxicities, drug activities and resistance. A model of treatment that builds on the lessons learned from the treatment of HIV has evolved to maximize success of treating dual infections. This review will address current strategies for the management of HIV in the setting of HCV and HBV co-infection and discuss future treatment directions and challenges.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
联合感染和联合治疗:在丙型肝炎和乙型肝炎患者中治疗艾滋病毒
由于共用传播途径,越来越多的人慢性感染艾滋病毒和丙型肝炎病毒和/或乙型肝炎病毒。随着HAART的出现,继发于肝炎合并感染的肝病已成为艾滋病毒感染者发病和死亡的主要原因。管理双重感染的需求日益增加,但由于合并症、重叠毒性、药物活性和耐药性,治疗变得复杂。基于从艾滋病毒治疗中吸取的经验教训,一种治疗模式已经发展到最大限度地成功治疗双重感染。本综述将讨论当前HCV和HBV合并感染情况下的HIV管理策略,并讨论未来的治疗方向和挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
HIV Therapy merges with Future Virology HIV-related lymphoma The intersection between HIV and syphilis in men who have sex with men: some fresh perspectives. Premature onset of cardiovascular disease in HIV-infected individuals: the drugs and the virus Cervical cancer prevention in HIV-infected women in resource-limited settings
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1