Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites

Adeleh Rezagholizadeh Shirvan, S. Sotoudeh, M. Tahmasebi
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Abstract

Fibrolamellar hepatocellular carcinoma (FLHCC) is a rare primary liver cancer that occurs in young adults, and its biology is not well known. We present a 21-year-old woman with metastatic liver cancer 6 months after undergoing embolization procedures for a typical hemangioma. The pathological investigation confirmed metastatic FLHCC. Despite liver mass resection and lung metastasectomy, after 3 months, the tumor recurred. In 18F-FDG PET-CT scan, lung, ovary, colon, and peritoneal invasions were reported. Unfortunately, the patient died a year after diagnosis due to a rapid progression and multiple unusual metastatic sites.
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纤维层状肝细胞癌:报告一例进展迅速且转移部位异常的罕见病例
纤维层状肝细胞癌(FLHCC)是一种罕见的发生于青壮年的原发性肝癌,其生物学尚不清楚。我们提出一个21岁的女性转移性肝癌6个月后,接受栓塞手术为典型的血管瘤。病理检查证实为转移性FLHCC。尽管进行了肝肿块切除术和肺转移切除术,但3个月后肿瘤复发。18F-FDG PET-CT扫描显示肺、卵巢、结肠和腹膜浸润。不幸的是,患者在诊断一年后由于快速进展和多个不寻常的转移部位而死亡。
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发文量
16
审稿时长
12 weeks
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