Automated Machine Learning Strategies to Damage Identification of Neurofibromatosis Mutations

A. Orjuela-Cañón, Juan Carlos Figueroa–García, Roman Neruda
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引用次数: 1

Abstract

Machine learning tools have been employed for problem solutions in bioinformatics. However, the parameters tuning of these models cam imply additional difficulties around the specific technique used to classify. In this work data from protein sequences was applied to three auto machine learning strategies to determine the type of mutation for the Neurofibromatosis disease. Results show that the parameters in the machine learning models were found automatically. In addition, these tools were relevant to determine relations between the amino-acids in the protein sequence.
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神经纤维瘤病突变损伤识别的自动机器学习策略
机器学习工具已被用于解决生物信息学中的问题。然而,这些模型的参数调整可能意味着围绕用于分类的特定技术的额外困难。在这项工作中,来自蛋白质序列的数据被应用于三种自动机器学习策略,以确定神经纤维瘤病的突变类型。结果表明,机器学习模型中的参数是自动找到的。此外,这些工具也适用于确定蛋白质序列中氨基酸之间的关系。
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