CONSERVATIVE TREATMENT AND FOLLOW-UP FOR ACUTE APPANDICITIS: IS EMERGENT SURGERY NECESSARY ?

S. Karakas
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Abstract

Introduction: Emergent operation is the accepted standart therapy of acute appendicitis. But conservative medical therapy is an emerging solution for acute appendicitis. We aimed to publish the conservative treatment experience of Inonu University Medical School, Department of General Surgery. Material and Method: Between January 2020 and January 2022, patients who had a clinical suspicous acute appendicitis with an Abdominal Ultrasonography or a computer tomography reporting a term ’appendicitis’ that referred to Emergency or General Surgery Department and also had a medical therapy with a non-operative approach were detected in the hospital data system. Patient demographics and clinical data analysed retrospectively. Results: Fifteen patients were detected within the 2 years period that had been received medical therapy for acute appendicitis. Median age was 32.0 (min:19 - max:70), median appendix diameter was 7.2 mm (min:5.5 - max:11.0). One patient was died due to Non-Hodgkin Lymphoma after 16 days of diagnosis of acute appendicitis. None of the patients required an operation during surveillance. Most frequent reasons for conservative treatment were not eliminating the diagnosis of pelvic inflammatory disease, inflammatory intestinal disease and urinary tract infections. Discussion and Conclusion: While some comorbidities can go along with acute appendicitis such as cardiac and systemic haematologic diseases, some of them mimic acute appendicitis such as pelvic inflamatory disease or inflamatory bowel diseases. Especially elder patients, who have a suspicous case, with a low CRP and Neutrophilia counts with an uncomplicated appendicitis, may benefit from antibiotherapy. More patients, that had an appendectomy history need to be evaluated on this aspect.
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急性阑尾炎的保守治疗和随访:是否需要紧急手术?
急诊手术是公认的治疗急性阑尾炎的标准方法。但保守的药物治疗是急性阑尾炎的新兴解决方案。我们的目的是发表猪野大学医学院普通外科的保守治疗经验。材料和方法:在2020年1月至2022年1月期间,在医院数据系统中检测到患有临床可疑急性阑尾炎的患者,腹部超声检查或计算机断层扫描报告“阑尾炎”一词,涉及急诊或普通外科,并且还接受了非手术方法的药物治疗。回顾性分析患者人口统计学和临床资料。结果:15例急性阑尾炎患者均在2年内接受内科治疗。中位年龄为32.0岁(最小19 -最大70),中位阑尾直径为7.2 mm(最小5.5 -最大11.0)。一名患者在诊断为急性阑尾炎16天后死于非霍奇金淋巴瘤。在监测期间,没有患者需要手术。保守治疗最常见的原因是未消除盆腔炎、炎症性肠病和尿路感染的诊断。讨论与结论:虽然一些合并症可以伴随急性阑尾炎,如心脏和全身血液学疾病,但其中一些类似急性阑尾炎,如盆腔炎或炎症性肠病。特别是老年患者,有可疑病例,低CRP和中性粒细胞计数,无并发症的阑尾炎,可能受益于抗生素治疗。更多有阑尾切除术史的患者需要在这方面进行评估。
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