Drug Utilization Study in a Tertiary Care Hospital of Tribal Area in South India

Ajay Khade, J. Khade, M. Bashir
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Abstract

Due to the irrational use of drugs, we are facing numerous problems of overuse, misuse, increased cost, antibiotic resistance etc. The present study was conducted in a tertiary hospital in which the patients are referred from surrounding rural and tribal areas. It is a retrospective study that included the patients admitted in clinical departments. A total of 200 patients (Males 41.5% and Females 58.5%) were included and their case records were reviewed. Most of the patients belong to age group < 30 years. The average No. of drugs per prescription was 4.76.Intravenous route was commonly used. The dose of the drug was inappropriate in 38% patients and inappropriate frequency in 3% cases. It was found that the most commonly prescribed group of drugs was antimicrobial agents (41.53%) with Ampicillin (53.01%) as the most commonly prescribed antimicrobial agent. Culture and Sensitivity was not conducted in any of the patient. Single antimicrobial agent was prescribed in 42% cases and combination of 2 antimicrobial agents in 38% cases. Thus, the drug utilisation in patients included in the study is not rational and hence, many recommendations were suggested.
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南印度部落地区某三级医院药物利用研究
由于药物的不合理使用,我们面临着过度使用、误用、成本增加、抗生素耐药等诸多问题。本研究是在一家三级医院进行的,病人是从周围农村和部落地区转诊过来的。这是一项回顾性研究,包括在临床科室入院的患者。共纳入200例患者,其中男41.5%,女58.5%。患者以年龄< 30岁者居多。平均没有。每张处方的药物数量为4.76种。静脉途径是常用的途径。38%的患者用药剂量不适宜,3%的患者用药频率不适宜。结果发现,最常用的抗菌药物是抗菌药物(41.53%),其中氨苄西林(53.01%)是最常用的抗菌药物。未对任何患者进行培养和敏感性检查。使用单一抗菌药物的占42%,联合使用2种抗菌药物的占38%。因此,纳入研究的患者的药物利用是不合理的,因此,提出了许多建议。
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