Prevalence of Hepatitis B Virus Infection in Blood Donors Based on Titer Hepatitis B Surface Antigen Examination (HBsAg)

S. D. Nurtjahyani, R. Handajani
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Abstract

Hepatitis B remains a global public health problem. Infection from hepatitis B virus (HBV) can be transmittedthrough a blood test or a blood transfusion. This study was conducted to identify the prevalence of HBV infectionin blood donors based on examination of HBsAg titers . Blood donors from Tuban Red Cross used as sample. Themethod used in this research is HBsAg titers examination performed by ELISA according to the procedureoutlined in the Kit. HBsAg titers positive mostly found in men. In men from 13 samples (8.67%) are HBsAg titerspositive of 150 samples while in woman all negative for HBsAg titers from 137 samples. The average titer positivewas 3.095 with a standard deviation of 0.187. While HBsAg titers negative have average of 0.03 with a standarddeviation of 0.14. This study showed that the prevalence of HBV infection in blood donors is most numerous inmen with HBsAg titers positive number of 8.67%.
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基于乙型肝炎表面抗原(HBsAg)检测的献血者乙型肝炎病毒感染率
乙型肝炎仍然是一个全球性的公共卫生问题。乙型肝炎病毒(HBV)的感染可以通过血液检查或输血传播。本研究旨在通过检测乙肝表面抗原滴度来确定献血者中乙肝病毒感染的流行程度。以图班红十字会献血者为样本。本研究使用的方法是根据试剂盒中概述的程序,通过ELISA进行HBsAg滴度检测。HBsAg滴度阳性多见于男性。在男性中,有13个样本(8.67%)在150个样本中HBsAg滴度呈阳性,而在女性中,137个样本中HBsAg滴度均为阴性。平均滴度为3.095,标准差为0.187。而HBsAg滴度阴性平均为0.03,标准差为0.14。本研究显示献血者中HBV感染率最高的人群是男性,其HBsAg滴度阳性率为8.67%。
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